Bain, James F. Conway, Binfeng Lu, Song Li. Targeting Xkr8 via nanoparticle-mediated in situ co-delivery of siRNA and chemotherapy drugs for cancer immunochemotherapy. Nature Nanotechnology, 2022; DOI: 10.1038/s41565-022-01266-2 发布于 2023-05-31 09:18・河北 癌症 纳米粒子...
Drug repurposing is the application of clinically approved drugs, with characterized pharmacokinetic properties and known side effect profiles, to new indications. The search for effective and durable treatment options for cancer therapy remains an unmet medical need. Drug repurposing has emerged as an ...
Dostarlimab or pembrolizumab plus chemotherapy in previously untreated metastatic non-squamous non-small cell lung cancer: the randomized PERLA phase II trial Several PD-(L)1 inhibitors have been approved or are in development for the treatment of NSCLC, showing promising efficacy and tolerable safe...
Immune checkpoint inhibitors are drugs that release the brakes on your immune system. Eight of these drugs are approved to treat cancer. They block the proteins PD-1, PD-L1, CTLA-4, and TF on the surface of immune cells, to let these cells go after the cancerous growth. PD-1 inhibitor...
Immunotherapy for Cancer Treatment Immunotherapy for Cancer Treatment: A Promising Treatment Approach Cancer is a disease that has been plaguing humanity for centuries. It is a complex disease that has been challenging to treat, and traditional treatment methods such as chemotherapy and radiation therapy...
Klencke B, Matijevic M, Urban RG, et al. Encapsulated plasmid DNA treatment for human papillomavirus 16-associated anal dysplasia: a phase I study of ZYC101. Clin Cancer Res 2002 May; 8(5): 1028–37 PubMedCASGoogle Scholar Sheets EE, Urban RG, Crum CP, et al. Immunotherapy of human ...
" Dr. Curiel said. "We've shown that if you test all your immune therapy just in young mice and young people, you'll never learn how it works in older patients — the ones most at risk for cancer. You might conclude that drugs don't work in aged hosts, when they do. But they ...
As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have recently gained attention as an important type of innate immune regulatory cell. NK cells can rapidly kill multiple adjacent cancer cells through non-MHC-restrictive effects. Although tumors may develop multip...
Herein, we discuss advances that have recently been made in cancer immunotherapy and the potential of this field to deliver effective treatment options for pancreatic cancer patients. Preclinical investigations, combining different types of therapies, highlight possibilities to enhance anti-tumor immunity ...
Immunotherapy drugs for cancer mainly includes immune checkpoint inhibitors, targeted monoclonal antibodies, cancer vaccines and cytokines.