Page 1 of 15 (page number not for citation purposes) BMC Immunology 2009, 10:10 http://www.biomedcentral.com/1471-2172/10/10 Background The ultimate role of the immune system in host defense is to eliminate infected and transformed cells [1,2]. A funda- mental feature of infected and...
Background: What is the major problem that prompted the study? Objective: What is the purpose of the study? Methods: How was the study done? Results: What are the most important findings? Conclusion: What is the most important conclusion drawn? In addition to written Abstracts...
Background: What is the major problem that prompted the study? Objective: What is the purpose of the study? Methods: How was the study done? Results: What are the most important findings? Conclusion: What is the most important conclusion drawn? In addition to written Abstracts,...
Background Engineered zinc-finger nucleases (ZFN) represented an innovative method for the genome manipulation in vertebrates. ZFN introduced targeted DNA double strand breaks (DSB) and initiated non-homologous end joining (NHEJ) after pronuclear or cytoplasmatic microinjection into zygotes. Resulting ...
Background. Although rare, adverse events may associate with anti-poliovirus vaccination thus possibly hampering global polio eradication worldwide. Objective. To design peptide-based anti-polio vacc...
Background CD8α is a surface glycoprotein typically found on a subpopulation of CTL [1]. CD8α enhances responses instigated through the TCR by binding MHC class I and signaling through the src kinase lck and the adaptor protein Linker for Activation of T cells (LAT) [2]. The classical ...
Clinical Background Skeletal muscle belongs to the largest organ system in the human body, accounting for one-third of body weight [1]. Its function is essential for the musculoskeletal system, which is responsible for coordinated movement and postural maintenance, as well as key functions in ...