Since then, we have continuously advanced the accuracy, sensitivity, and reproducibility of the IHC assay-expanding our portfolio with cutting-edge products to support every step of the IHC workflow. Why Choose
In this exploratory post-hoc analysis, we evaluated the analytical concordance of SP142 with 2 other PD-L1 IHC assays, and their ability to predict clinical activity. Methods Available samples from IMpassion130 were evaluated for PD-L1 status using VENTANA SP142 or SP263 IHC assay (IC ≥ 1%...
mutations can be found in various solid tumors. But accurate and reliable screening formutation that is compatible for clinical application is not yet available. In this study, we used an automated immunohistochemistry (IHC) staining coupled with mouse monoclonal anti-BRAF V600E (VE1) primary ...
In this chapter, we discuss various facets of IVD IHC assay development (such as primary antibody selection and the importance of assay controls) from an industrial research perspective. We then discuss the additional considerations that apply to IHC tests intended for use as complementary or ...
Explore all of our IHC assay kits and reagents for Diagnostics Our ihcDirect products are listed forin vitrodiagnostics (IVD) use and provide IHC results at room temperature in as little as 10 minutes on frozen sections. → Shop For RESEARCH ...
Detection of labeled primary improves assay linearity over both chromogenic and fluorescent IHC. Multiplexed mass-tagged incubated simultaneously with tissue do not appear to cross-interfere, and because the mass tags do not degrade, samples are stable indefinitely. The imaging resolution of multiplexed ...
IHC-plus™ Antibodies PathPlus™ Cancer Pathology Antibodies Primary Antibodies Secondary Antibodies Isotype Controls ELISA and Assay Kits Our traditional Sandwich, Competitive EIA, and Direct ELISA kits provide a means to quantitatively measure thousands of targets of interest, while our Cell-Based an...
The primary antibody is a critical component of any IHC assay and has a direct effect on data quality. The determination of target specificity in IHC analysis requires multiple validation steps. CST offers over 700 recombinant monoclonal antibodies that have been rigorously validated for IHC using fo...
Immunohistochemistry(免疫组化,IHC)是一种利用抗原-抗体相互作用来检测组织切片中抗原的分布和定位的技术,已广泛应用于肿瘤学、病理学、免疫学等临床领域。IHC实验步骤较为繁杂,从组织取样到最终显色封片的每个环节都有需要注意的地方,在实验过程中多会遇到高背景、结果重复性差和出现假阳性/假阴性结果等问题。 ★ 主...
Cofactor’s ImmunoPrism assay was designed to overcome some of the challenges of immunohistochemistry in cancer diagnosis. ImmunoPrism is built on Predictive Immune Modeling, which uses multidimensional modeling of RNA to better understand and diagnose cancer. Unlike IHC or multiplex IHC, ImmunoPrism le...