The term herd immunity refers to a reduction in the likelihood of someone catching a specific infectious disease because a significant proportion of the people in that person's community are immune to it. If you are less likely to come in contact with an infectious person, you're less likely...
Herd immunity can prevent sustained disease spread in populations, thereby protecting susceptible individuals from infection. It is applicable, however, only to infectious diseases that can be spread by human contact. The percentage of the population that must be immune to produce herd immunity differs...
These include newborns, people allergic to certain vaccines, people with weakened or failing immune systems, or elderly with chronic diseases. This is where herd immunity comes into play, providing indirect protection to these groups. Optimal herd immunity via vaccination also counteracts waning immunity...
The epidemic has radically changed the lives of many people, and their understanding and emphasis on healthcare have become more profound and popular among people than ever before. In addition, the word "immunity" also often a...
REVIEWS Studying immunity to zoonotic diseases in the natural host — keeping it real Andrew G. D. Bean1, Michelle L. Baker1, Cameron R. Stewart1, Christopher Cowled1, Celine Deffrasnes1, Lin‑Fa Wang1,2 and John W. Lowenthal1,3 Abstract | Zoonotic viruses that emerge from...
Complacencyabout vaccine-preventable diseases, combined with concerns over the effects of vaccination, led to decreasing levels of vaccination coverage in some areas of the world. As a consequence, not only were individuals susceptible to vaccine-preventable diseases, but, at population levels, vaccinati...
MOE Innovative Center for New Drug Development of Immune Inflammatory Diseases, Shanghai, China Jiaxu Zhao, Rui Zeng, Xiaohui Li, Haibao Peng, Hao Chen, Ye Zhang, Yang Huang, Wenhan Chen & Yudan Chi Key Laboratory of Metabolism and Molecular Medicine of the Ministry of Education, Shanghai, ...
because the disease spread within the population is very limited. Communities with lower vaccine coverage may have outbreaks of vaccine-preventable diseases because the proportion of people who are vaccinated is below the necessary herd immunity threshold. In addition, the protection offered by vaccines...
Over the past two decades, new viral diseases have emerged and become a major public health threat worldwide. In December 2019, an outbreak of a new highly contagious infection caused by SARS-CoV-2 emerged in Wuhan, China, which subsequently swept the world and took the form of a pandemic...
Because T cell homeostasis maintains constant numbers of T cells in the periphery, even the age-associated decreased thymic-output of naive cells is blocked, and the shrinkage of the naive T cell repertoire contributes to increased susceptibility to newly-encountered infectious diseases. IM, ...