The cell types involved in the innate immune response are phagocytic cells: neutrophils, macrophages, natural killer cells, basophils, and others. As a leader in antibody development, CST has developed a wide array of highly effective antibodies against proteins involved in innate immunity such as ...
The immune system comprises diverse specialized cell types that cooperate to defend the host against a wide range of pathogenic threats. Recent advancements in single-cell and spatial multi-omics technologies provide rich information about the molecular state of immune cells. Here, we review how the...
In the study, the BGU researchers used gene expression data from 11 types of immune cells from male and female mice. Surprisingly, in one of the cell types, called macrophage, significant differences between males and females were found. The main difference was in genes associated with interferon...
from some or all of ImmGen 11 cell set, whose cell types are shown in the tree on the top. On the bottom, details of the four datasets used. PC peritoneal cavity, Sp spleen, CNS central nervous system, ATAC-
“Our multi-tissue immune cell atlas is a step towards understanding how the immune system functions throughout the entire body and is an important contribution towards the Human Cell Atlas. In addition to creating a new resource for researchers to classify different cell types, our work will ...
IMMUNE SYSTEM I. The immune system is a complicated array of cellular and biochemical components designed to discriminate self from nonself. II. Both the antigen-specific and antigen-nonspecific components of the immune system protect the individual from infectious agents, neoplastic cell growth, and...
We completed a deep mapping of the immune system in adults with DS using mass cytometry to evaluate 100 immune cell types, which revealed global immune dysregulation consistent with chronic inflammation, including key changes in the myeloid and lymphoid cell compartments. Furthermore, measurement of ...
APCs specific to the spleen regulate the T and B cell response to these antigenic targets in the blood. This review will focus on cell types, cell organization, and immunologic functions specific to the spleen and how these affect initiation of adaptive immunity to systemic blood-borne antigens...
lumen, while keeping the full capability to control colonization by pathogenic bacteria1. Variations of this equilibrium induce the recruitment and expansion of several immune cell types contributing to initiate and propagate intestinal inflammation, or to restore homeostasis by activating tolerogenic ...
The immune system is distinctive for being a distributed system. It is not fixed to a single localized organ in the body, but rather is made up of numerous specialized cell types that must adaptably organize their intercellular connections to respond to pathogens and other threats wherever they ...