A three-way interaction between pregnancy hormones, the immune system and our microbiota is now emerging. Recent evidence suggests that microbial alterations seen during pregnancy may help maintain homeostasis
The gut microbiome lies at the intersection between the environment and the host, with the ability to modify host responses to disease-relevant exposures and stimuli. This is evident in how enteric microbes interact with the immune system, e.g., supporting immune maturation in early life, affecti...
Fungi are an integral part of the human microbiota interacting with the immune system and affecting human physiology. The human mycobiota is composed of 390 different fungal species belonging to the phylaAscomycota, Basidiomycota, andZygomycota1, which are required for microbial community structure, m...
Recent years have exhibited an increasing number of works on the modulation of the microbiome by the immune system [1–3] and the effect of the microbiome on the healthy development of immunity [4, 5] as well as on autoimmune disorders [6–8]. Groundbreaking research on these topics was ...
cDNA was generated from 1 μg of isolated RNA from ectocervical, endocervical, and vaginal cells using the High-Capacity cDNA Reverse Transcription Kit (Applied Biosystems, Thermo Fisher Scientific). qPCR was performed on the 7900HT Real-Time PCR System (Applied Biosystems) using the TaqMan Unive...
primarily under the influence of sex hormones, which make it distinct from other mucosal sites. Here, we discuss the various components of the immune system that are present in both the male and female reproductive tracts, including innate soluble factors and cells and humoral and cell-mediated ...
2021. Biogeography of the relationship between the child gut microbiome and innate immune system. mBio 12:e03079-20. https://doi.org/10.1128/mBio.03079-20. This article is a direct contribution from William W. Mohn, a Fellow of the American Academy of Microbiology, who arranged for and ...
Cancer-supporting cells control their neighbors’ behavior using an often-overlooked protein delivery system. Shielding From Allergies: It’s Not Just About Microbes Mariella Bodemeier Loayza Careaga, PhD|Feb 7, 2024|4min read Clean and dirty mice respond similarly to allergens, challenging the idea...
and immune training, with important consequences for human health. Only a few studies have directly examined the interactions between the gut microbiome and the immune system during pregnancy, and the subsequent effect on offspring development. In this Review, we aim to describe how the maternal ...
and immune training, with important consequences for human health. Only a few studies have directly examined the interactions between the gut microbiome and the immune system during pregnancy, and the subsequent effect on offspring development. In this Review, we aim to describe how the maternal ...