A three-way interaction between pregnancy hormones, the immune system and our microbiota is now emerging. Recent evidence suggests that microbial alterations seen during pregnancy may help maintain homeostasis and aid the required physiological changes occurring in pregnancy. However, these same ...
Recent years have exhibited an increasing number of works on the modulation of the microbiome by the immune system [1–3] and the effect of the microbiome on the healthy development of immunity [4, 5] as well as on autoimmune disorders [6–8]. Groundbreaking research on these topics was ...
The gut microbiome lies at the intersection between the environment and the host, with the ability to modify host responses to disease-relevant exposures and stimuli. This is evident in how enteric microbes interact with the immune system, e.g., supporting immune maturation in early life, affecti...
Similarly, the composition and diversity of the vaginal microbiome have been shown to be highly associated with cervicovaginal (CV) health and disease [7]. The vaginal microbiome has been well characterized in both nonpregnant and pregnant individuals using high-throughput 16S rRNA gene sequencing, ...
Fungi are an integral part of the human microbiota interacting with the immune system and affecting human physiology. The human mycobiota is composed of 390 different fungal species belonging to the phylaAscomycota, Basidiomycota, andZygomycota1, which are required for microbial community structure, ...
A meta-analysis of 32 studies showed that the immune system within the vagina ebbs and flows, depending onmenstrual-cyclestage. The analysis identified 53 distinct messages that immune cells sent to one another. Cells in the body talk to each other by making molecules calledcytokines, which can...
Lactobacillus species dominance of the vaginal microbiome is a hallmark of vaginal health. Pathogen displacement of vaginal lactobacilli drives innate immune activation and mucosal barrier disruption, increasing the risks of STI acquisition and, in pregn
microbiome and the host immune system, we aim to uncover novel therapeutic strategies that enhance the efficacy of cancer treatments. Additionally, this review addresses the existing challenges and future prospects within this burgeoning field, advocating for the integration of microbiome research into ...
Researchers employ peripheral blood mononuclear cells (PBMCs) in clinical and academic applications related to the immune system and regenerative medicine. Opinion: Harnessing Microglia Cells to Stave Off Neurodegeneration Kristine ZengelerandThe Conversation | Dec 9, 2022 | 5 min read Dialing up the ...
(25), a reciprocal relationship between the colonizing intestinal bacteria and the mucosal immune system is stressed. She emphasizes the contri- bution that mucosal immune defenses have made in defining the composition of intestinal bacteria, not only within the intes- tinal lumen, but also on the...