In this chapter, we will discuss the host immune response to influenza virus based on current data obtained fromin vitroandin vivosystems. The interaction of the virus with innate immune mechanisms will be discussed, with a focus on the mechanisms of influenza evasion. The transition between ...
After clearance, no virus exists in the lung, but the cells that used to be infected remain. The team found that those "survivor cells" actually divide and replenish themselves at a faster rate than uninfected cells. "One can imagine that if Tcellskilled every infected cell, like people on...
Specific immunity to influenza is associated with a systemic immune response (serum haemagglutination inhibition antibody), local respiratory immune response (virus-specific local IgA and IgG antibodies in nasal wash), and with the cell-mediated immune response. Both inactivated and live influenza vaccin...
The study explored influence of biological sex on development of humoral immune response to seasonal trivalent whole inactivated virus (WIV) and split virus (SV) influenza vaccines in outbred Swiss mouse model. To this end, mice of both sexes were immunized with WIV (WIV mice) and SV vaccines...
bJiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou University, Yangzhou, China; cJiangsu Key Laboratory of Zoonosis, Yangzhou, China ABSTRACT Influenza A virus is a negative-sense single-stranded RNA virus that belongs to Orthomyxovirid...
Introduction Human host immune response following infection with the new variant of A/H1N1 pandemic influenza virus (nvH1N1) is poorly understood. We utili... JF Bermejo-Martin,ROD Lejarazu,T Pumarola… - 《Critical Care》 被引量: 541发表: 2009年 Effects of IL-12 on the response and susce...
AIM2 inflammasome is critical for influenza-induced lung injury and mortality. J. Immunol. 198, 4383–4393 (2017). Article CAS PubMed PubMed Central Google Scholar Thomas, P. G. et al. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the ...
The antibody response (determined using the single radial haemolysis in gel technique) to inactivated whole-virion trivalent influenza vaccine [A/Leningrad/360/86(H3N2), A/Taiwan/5/87 and B/Ann Arbor/1/86], recommended for the 1987–88 winter season in Italy, in 49 elderly (age <IMG titl...
Influenza virus infection induces a narrow antibody response in children but a broad recall response in adults. mBio 11, e03243-19 (2020). PubMed PubMed Central Google Scholar Channappanavar, R., Zhao, J. & Perlman, S. T cell-mediated immune response to respiratory coronaviruses. ...
Study selection: Articles were reviewed and selected on the basis of relevance to subject matter. Results: In this review, we first introduce the influenza virus, its nomenclature, and the concepts of antigenic drift and shift. Second, we discuss the status of currently licensed influenza virus ...