Gluten-related disorders in humans comprise different entities, including coeliac disease. Patients typically have measurable titers of anti-gliadin IgG or IgA (AGAs) and anti-transglutaminase-2 IgA (TG2). In addition to intestinal symptoms, human patients often show various neurological complications....
thereby enhancing protection from the associated disease. In recent years, advances in our understanding of the innate and adaptive immune systems have allowed for the development of a number of novel adjuvants with differing mechanisms of action. Herein,...
However, as RABV can stay at the entry site of infection for days or weeks before arriving at the central nervous system and causing symptoms, immunizations either prior to or soon after exposure can be an effective strategy against the disease. Ideal rabies vaccines that provide successful post...
In addition, the migration of B cells to lymph nodes also relies on other receptors, such as C-X-C-chemokine receptor 4 (CXCR4) and CXCR5 [87, 88]. The expression levels of CCR7 and CCL21 peak before and after the onset of nocturnal disease, leading to the recruitment of B cells. ...
Causes of the disease in dogs and cats are tabulated and classified in groups as hereditary, primary, metabolic, neoplastic , and those due to infections and toxicity. Common symptoms include anorexia, depression and asthenia and less frequently vomiting, diarrhoea, syncope and collapse. ...
Cell-mediated and humoral immune response in naturally and experimentally infected dogs was studied using crude and pure antigens. Both types of infections induced severe signs of visceral disease, but the symptoms observed in natural infections were more pronounced than in experimental infections. In ...
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9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook immune reaction Thesaurus Medical Financial Encyclopedia Wikipedia n. The reaction resulting from the recognition and binding of an antigen by its specific antibody or by a previously sensitized lymphocyte. Also called...
In normal dogs, AAV-mediated Cas9 expression induces similar, though milder, immune responses. In contrast, other therapeutic (micro-dystrophin and SERCA2a) and reporter (alkaline phosphatase, AP) vectors result in persistent expression without inducing muscle inflammation. Our results suggest Cas9 ...
VL manifests across a spectrum of clinical presentations, varying from asymptomatic to severe and fatal disease, particularly when left untreated5. Symptoms such as recurrent fever, hepatosplenomegaly, asthenia, anorexia, and weight loss are frequently reported during active disease6,7. Moreover, signs...