This study investigated the isolation and biological properties of microvesicles derived from human immortalized cell lines of adipose tissue-derived MSC (ATMSC) and EPC origin. We analyzed the content of cytokines and trophic factors of both populations of microvesicles, the presence of proangiogenic ...
Graf, MD, MSc*Wolfgang Zink, MD, DEAAAnesthesia & AnalgesiaHofmann, P., Metterlein, T., Bollwein, G., Gruber, M., Plank, C., Graf, B. M., et al. (2013). The myotoxic effect of bupivacaine and ropivacaine on myotubes in primary mouse cell culture and an immortalized cell line....
Human mesenchymal stromal cell (MSC)-derived extracellular vesicles (EV) revealed neuroprotective potentials in various brain injury models, including neonatal encephalopathy caused by hypoxia–ischemia (HI). However, for clinical translation of an MSC-EV therapy, scaled manufacturing strategies are required...
They are a type of mesenchymal stem/stromal cell (MSC) capable of proliferating and differentiating into islet-like cells. These cells are useful in providing insight into human β cell development cycle and are an ideal model for research in cell replacement therapies of diabetes. Procedure ...
We derived several stable immortalized \\\{MSC\\\} cell lines. One of these, called pBMC-2, was chosen for further characterization. After "in vitro" stimulation of both primary or immortalized cells with 5-azacytidine, we obtained different percentages (30%鈥 50%) of cells with cardiomyocyte...
产品名称: Immortalized-Human-Cord-Blood-Mesenchymal-Stromal-Cells-with-RFP-(cbMSC-hTERT-R 产品型号: 产品展商: ABM产品文档: 无相关文档 简单介绍 Immortalized-Human-Cord-Blood-Mesenchymal-Stromal-Cells-with-RFP-(cbMSC-hTERT-RFP)-Immortalized-Human-Cord-Blood-Mesenchymal-Stromal-Cells-with-RFP-(cbMSC...
The validity for using these immortalized cells for cell culture metabolic study relies on the maintenance of hepatocyte phenotypes as represented by a panel of specific markers. Hepatocyte-like cells from various MSC sources exhibited different intensities of hepatocyte specific markers[9]. We ...
Primary MSCs were immortalized by transduction with simian virus 40 large T antigen (SV40LT), and the resulting iMSC and iAAT-MSC lines were analysed for proliferation, senescence, phenotype and multi-differentiation potential. Subsequently, apoptosis and ferroptosis pathways were investigated by ...
Generation of HM3.B10 (B10) immortalized human bone marrow mesenchymal stem cell (MSC) line.Atsushi, Nagai
Stem cell supernatantsChronic woundPhenotypic characterization of the HATMSC cell lines. The mean fluorescent intensity of HATMSC1, HATMSC2, HATMSC2D10, and HATMSC2F10 cells was reported on the -axis. Black line curves represent isotypic control; red fields represent fluorescent peaks...