aIllustration of self-immolative PTC following H2S activation. H2S-triggered cycle amplification takes advantage of the produced COS, which is then rapidly hydrolyzed to H2S by CA. ABA: 4-aminobenzyl alcohol, COS: carbonyl sulfide, CA: carbonic anhydrase, PEG: methoxy poly(ethylene glycol).bThe ...
Here we present a "click to self‐immolation" strategy based on aroyl azide‐capped SIP precursors, enabling the facile construction of diverse SIPs with different trigger units through a Curtius rearrangement and alcohol/thiol‐isocyanate "click" reaction. This strategy is also app...