immediate early genes原理 它们的激活通常不依赖于新的蛋白质合成。IEGs 的表达能够快速响应各种外界信号。这些基因在神经生物学中具有重要作用。可以参与神经元的可塑性和记忆形成过程。IEGs 的调控机制复杂多样。包括转录因子的结合以及染色质的修饰。它们能快速改变细胞的生理状态。部分 IEGs 编码转录因子,进一步调控...
即刻早期基因(Immediate early genes , IEGs)在受到各种各样的细胞刺激时,它们会短暂而迅速地被激活。它们代表了一种长期的反应机制,在任何新的蛋白质合成之前,在对刺激的第一轮反应中,在转录水平上被激活。因此,IEGs不同于“晚期反应”基因,后者只有在早期反应基因产物合成后才会被激活。因此,...
Immediate early genes (IEGs) that get rapidly and transiently expressed following neuronal stimulation provide a powerful tool for detecting behavior-related neuronal activity in vertebrates. In social insects, like honey bees, and in insects in general, this approach is not yet routinely established,...
The identification of sparse neuronal populations recruited in response to drug exposure has benefited greatly from the study of immediate early genes (IEGs) whose induction is critical in initiating plasticity programs in recently activated neurons. In particular, the development of technologies to ...
Immediate early genes (IEGs) are a class of genes that show rapid and transient but protein synthesis-independent increases in expression to extracellular signals such as growth factors and neurotransmitters. Many IEGs code for transcription factors that have been suggested to govern the growth and ...
Immediate early genes (IEGs)PsychostimulantOpioidAlthough some of the clinical manifestations of substance use disorders might be superficially similar, it is highly likely that different classes of abused drugs including opioids (heroin, morphine, and oxycodone, other opioids) and psychostimulants (...
立早基因(immediate early genes,IEGs)是一组在受到一系列外界刺激后迅速并且短暂激活的基因。这些基因...
1.Objective To explore the regulative action of IEGs when the nicotinic acetylcholine receptors (nAChRs) of PC12 cells were activated by anatoxin-a.目的探讨即刻早期基因在类毒素A激活PC12细胞烟碱受体过程中的调控作用。 4)immediate early genes即刻早期基因 1.In order to study the role of immediate ...
Immediate-EarlyResponseGenes(IEGs)qpcrarray涵盖的具体项目? Immediate-EarlyResponseGenes(IEGs)qpcrarray参考哪些标准? Immediate-EarlyResponseGenes(IEGs)qpcrarray检测周期多久呀? Immediate-EarlyResponseGenes(IEGs)qpcrarray对样品有什么要求? Immediate-EarlyResponseGenes(IEGs)qpcrarray如何收费? Immediate-EarlyRespo...
Cellular immediate-early genes (IEGs) share a close structural homology with some viral oncogenes. In the eukaryotic genome these counterparts of oncogenes have been termed proto-oncogenes. Recent advances in cellular biology have identified the activation and deactivation of IEGs as molecular mechani...