The gastric acid plays a crucial role in the process of food digestion; however, its regurgitation in to the esophagus leads to irritation. The lower esophageal sphincter, a circular muscle located at the bottom of the throat, contracts as a way to prevent the reflux of gastric acid and food...
The present inventors identified the need to be able to administer a pain relieving/anti-inflammatory drug to a subject before the subject went to bed, but recognised that often subjects feel pain immediately upon waking and if they were to take pain relief once awake, there would be a period...
Esomeprazole delayed release tablets (ESO) are one of the most effective treatments for acid-related disorders. The purpose of this study is to compare the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of an immediate-release capsule formulation containing esomeprazole 20 mg and sodium bica...