Immature DC are considered to be specialized in antigen capture and processing, whereas mature DC present antigen and have an increased T-cell stimulatory capacity. Therefore, the consensus has been to electroporate DC before maturation. We show that the transfection efficiency of DC electroporated...
Conclusions: Considering that the ability of DCs to regulate immunity is dependent on DC maturation, results suggest that predominance of imDCs appears to be involved in AgP pathogenesis, probably due to lack of ability to induce immune cell activation. Further studies are necessary to elucidate ...
Therefore, rat marrow progenitors can generate large numbers of immature DC, with abundant intracellular MHC class II compartments, and potent, stimulatory, mature DC.doi:10.1002/(SICI)1521-4141(199803)28:03<811::AID-IMMU811>3.0.CO;2-SMia Talmor...
Mature CD10+ and immature CD10- neutrophils present in G-CSF-treated donors display opposite effects on T cells. Mature CD10+ and immature CD10- neutrophils present in G-CSF-treated donors display opposite effects on T cells. Blood (2017) 129:1343-56. doi: 10.1182/blood-2016-04-713206Mar...
Cryopreservation is critical in reducing redundant operations and also in quality control in dendritic cell (DC) therapy. Full maturation and efficient homing of DCs to T cell-region constitute a crucial aspect of DC immunotherapy; however, the in vivo m
Repetitive stimulation of naive CD4+ T cells with allogeneic immature DC, in the absence of immune-modulating agents, results in the differentiation of naive T cells into nonexpanding CD4+/CD25+ T cells.19 This T-cell population induced by immature DCs in vitro, produces high amounts of IL-...
树突细胞(DC)是先天免疫系统连结至适应性免疫系统和平衡自我和非自我之间的适应性反应有力专业的抗原呈递细胞。根据不同的成熟信号,未成熟树突状细胞可被选择性地刺激分化成免疫原性或耐受性的DC。免疫原性树突状细胞的抗原特异性T细胞克隆扩增提供扩散信号;同时致耐受性树突细胞调节由抗原特异性T细胞缺失或调节性T细胞的...
2) Immature DC 不成熟DC 例句>> 3) immaturity [英][imə'tjuəriti] [美][ɪmə'tjʊrətɪ] 不成熟性 1. Socialist society s immaturity is the root cause why our constitution was often revised. 社会主义社会的不成熟性是我国宪法不断修改的根本原因。4) immaturecotton 不...
Kovanci E,Kovacs T,Moretti E,et al.FISH assessment of aneuploidy frequencies in mature and immature human spermatozoa classified by the absence or presence of cytoplasmic retention. Human Reproduction . 2001Kovanci E, Kovacs T, Moretti E, Vigue L, Bray-Ward P, Ward DC & ...
FIG. 1. Surface phenotype of human iDC and mDC. iDCs were prepared by culturing these monocytes for 5 days in AIM medium containing 10% FCS in the presence of 400 U/ml GM-CSF and 400 U/ml IL-4. mDCs were obtained by further culturing of immature DC sample with 50 ng/ml TNF-␣...