Please refer to the ASHP Drug Shortages Resource Center for information on shortages of one or more of these preparations.Imiquimod Routes Dosage Forms Strengths Brand Names Manufacturer Topical Cream 5% Aldara (with benzyl alcohol and parabens) Graceway ...
Imiquimod cream, 3.75% is indicated for the topical treatment of clinically typical visible or palpable, actinic keratoses (AK) of the full face or balding scalp in immunocompetent adults. 1.2 External Genital Warts Imiquimod cream, 3.75% is indicated for the treatment of external genital and peri...
It is not likely that other drugs you take orally or inject will have an effect on topically applied Aldara. But many drugs can interact with each other. Tell your doctor all prescription and over-the-counter medications and supplements you use. Aldara During Pregnancy and Breastfeeding During ...
Various healthcare products for treating the skin are known. The products may be purely cosmetic compositions, essentially cosmetic compositions with medical benefits, over the counter drugs or prescription drugs. Healthcare products, such as skincare products, comprising a pharmaceutically compound can b...
RUT and dexamethasone acetate (DXM) were purchased from Sigma-Aldrich (MO, USA), and 5% imiquimod cream (Aldara) was purchased from 3 M pharmaceuticals (UK). RUT cream (0.1%, 0.5% and 1%) and 0.075% DMX cream were produced by the department of pharmacy, the Second Xiangya Hospital of...
Aldara application to the skin of mice for 1 week leads to an increase in IL-10-producing B10 cells, a decrease in inflammatory cytokines by T cells and to a massive differentiation of splenic B cells to Ab-producing cells. In vitro, IMQ treatment of splenic B cells induces IL-10 RNA ...
Aldara Label/Package Insert (Mar. 2007). Aldara Label/Package Insert (Apr. 2009). Pacer Docket Sheets as of Nov. 29, 2010; Graceway Pharmaceuticals, LLC and 3M Innovative Properties Company v. Perrigo Company et al., U.S. District Court, District of New Jersey, Case No. 2:10-cv-...
Because surgical excision was not suitable as a first-line treatment owing to the size of the lesion, daily application of 5% imiquimod cream (Aldara) was initiated. After 1 week of treatment, the lesion became erosive. Thereafter, the frequency of therapy was reduced to 2 to 3 times weekly...
The IMQ model of acute skin inflammation has become the most widely used mouse model in this category over the past several years19. TLR7 sensing via pDC is thought to drive massive IFN-I expression within 6 hours that contributes to the induction of multiple inflammatory markers and histologi...
The increased susceptibility to IMQ-induced psoriasis of GILZ-Tg mice was significantly associated with skin-specific over-activation of TGF-β1-mediated signaling via SMAD2/3. Our findings demonstrate that GILZ may behave as pro-inflammatory protein in certain tissues and that, similar to prolonged...