The highly diastereoselective synthesis of substituted 1,2,3,4,4a,9,9a,10-octahydroacridines 7, 8 with five stereogenic centers has been achieved by domino imine condensation/intramolecular polar [4π+ + 2π]-cycloaddition of anilines 3 and ω-unsaturated aldehydes 4. The transformations which ...
Preparation of .alpha.-Methylene and .alpha.-Ethylidene .beta.-Lactams via the Ester Enolate-Imine Condensation Using .beta.-(Dialkylamino) Esters as Start... A new, simple procedure for the preparation of appropriately substituted alpha-methylene and alpha-ethylidene beta-lactams via the ester ...
ChemInform Abstract: The Enolate-Imine Condensation Using Lithium Dianion of 3- Hydroxybutanoate and N-Acylaldimines: Enhanced Stereoselectivity by Added Lithium Chloride.heterocyclic 4‐membered ringsstereochemistry (general, optical resolutionChemInform is a weekly Abstracting Service, delivering concise ...
We developed a vinyloxyborane-imine condensation reaction and applied it to a synthesis of thienamycin. The vinyloxyborane prepared from 6 by the use of 9-BBN triflate and diisopropylethylamine reacted with the imine 5 to give the β-benzylamino thiol ester 7, which was converted to the β...
In exploration of imines that undergo Cu-catalyzed 2 + 2 IOPC with norbornene, we found that aldimines from N-allyl amine condensation with isobutyraldehyde, 3-(methylthio)propanal, or melonal were all successfully converted to their corresponding azetidines, 2, 3, and 4, respectively, ...
et al. Aminal-linked covalent organic frameworks through condensation of secondary amine with aldehyde. J. Am. Chem. Soc. 141, 14981–14986 (2019). Article CAS PubMed Google Scholar Li, X. T. et al. Construction of covalent organic frameworks via three-component one-pot Strecker and ...
25. Condensation Chemistry(154) 26. Amines(129) 27. Heterocycles(0) 28. Carbohydrates(163) 29. Amino Acids(82) 30. Peptides and Proteins(1) 31. Catalysis in Organic Reactions(0) 32. Lipids (0) 33. The Organic Chemistry of Metabolic Pathways(0) 34. Nucleic Acids(0) 35...
Quinoneiminedyesareproducedbytheconcurrentoxidationofpara-aminophenolsandphenolsorpara-diaminesandamines,aswellas bythecondensationofpara-nitrosophenolswithphenolsorpara-nitrosamineswithaminesorphenols.Dyes(III),(IV),(V),and(VI)haveanintenseblueorgreencolorbutarenotsufficientlystable;theyareusedasintermediateproduc...
(organic chemistry) Any of a class of unsaturated nitrogen compounds, having the general formula R2C=C(R)-NR2, prepared by the condensation reaction of an aldehyde or ketone with an secondary amine; they are the tautomeric forms of imines. Enamine An amine containing the double bond linkage ...
A totally convergent and very short (three steps) synthesis of (±)-jamtine was described. The key step of this sequence was the condensation of 6,7-dimethoxy-3,4-dihydroisoquinoline and tetrahydrophthalic anhydride under microwave activation which occurred in good yield and high diastereomeric se...