The IMGT/HLA Database is a specialist database for sequences of the human major histocompatibility (MHC) system. It includes all the HLA sequences officially recognised and named by the WHO Nomenclature Committee for Factors of the HLA System. The database provides users with online tools and ...
HLA II 型基因主要包含了DR, DQ, DP, DO, DM系列基因 4. 其他基因 包含了HFE,MICA,MICB,TAP1,TAP2这几个基因 对于不同的Allel, 除了WHO委员会指定的标准命名外,还提供了一个HLA编号,示意图如下 在如下链接中,可以查看每个allel的详细情况 https://www.ebi.ac.uk/ipd/imgt/hla/docs/version_r3330.htm...
该数据库还提供了FTP服务,用于下载不同Allel的基因或者蛋白序列,链接如下 ftp://ftp.ebi.ac.uk/pub/databases/ipd/imgt/hla/ 在FTP中,提供了fasta,msf,pir等多种格式,通常下载fasta就可以了,同时提供了dna, rna, protein 3个不同水平的序列
在HLA领域内,术语“等位基因”指的是点突变、插入和删失的组合,因此,与单个参考序列相比,每个等位基因可以由多个不同的变异位置组成。这些等位基因信息储存在IPD-IMGT/HLA数据库中。IPD-IMGT/HLA 数据库(https://www.ebi.ac.uk/ipd...
HLA全称human leukocyte antigen, 表示人类白细胞抗原,是编码主要组织相容性复合体(MHC)的基因,位于6p21.31的区域...蛋白质,包括DR, DP, DQ等基因,HLA-III型基因,包含了C2,C4,BF等补体基因,还包括其他一些基因,分布图如下某些特定的HLA蛋白与疾病密切相关,比如HLA-B27在临床检测中作为僵直...
The IMGT/HLA Database (www.ebi.ac.uk/imgt/hla/) specialises in sequences of polymorphic genes of the HLA system, the human major histocompatibility complex (MHC). The HLA complex is located within the 6p21.3 region on the short arm of human chromosome 6 and contains more than 220 genes ...
Different IMGT/HLA database versions can be installed using the Install HLA database wizard on the settings dashboard. Note, that not all database versions are available, only those which were validated by the Omixon team. If you have to use a specific, unavailable IMGT/HLA database version...
IMGT/HLA数据库，怎么查询HLA等位基因？请会的宝宝帮忙解答下，感激涕零。
IPD-IMGT/HLA is a constituent of the Immuno Polymorphism Database (IPD), which was developed to provide a centralised system for the study of polymorphism in genes of the immune system. The IPD project works with specialist groups of nomenclature committees who provide and curate individual sectio...
TheIMGT-HLAdatabase 系统标签: hlaimgtdatabaseallelessubmissionsnomenclature TheIMGT/HLAdatabase JamesRobinson 1 ,KavitaMistry 1 ,HamishMcWilliam 2 ,RodrigoLopez 2 ,PeterParham 3 andStevenG.E.Marsh 1,4, * 1 AnthonyNolanResearchInstitute,RoyalFreeHospital,PondStreet,Hampstead,London,NW32QG, 2 Externa...