pastoris . Constitutive overexpression of the five selected secretion factors did not have an obvious negative effect on cell growth of the IL2-HSA secreting strain. Individual co-overexpression of Ero1, Kar2, Pdi1, Sec1 and Sly1 improved the secretion level of IL2-HSA to ~2.3-, 1.9-, ...
.Several excipients was tested for the effect to protein stability under elevated storage temperature and photostability test was taken,the protein was proven to be stable throughout photo-stability test,after a 6month-long storage NaCl is considered to be a better excipient for ...
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The stability of interleukin2-HSA fusion protein was examined in different pH and buffer solution environments using SDS-PAGE and SE-HPLC.A pH-5 solution of Acetic acid Sodium acetate buffer is found to be more suitable for IL2...