蛋白纯度:IL17A & IL17F Heterodimer protein purity > (65.3+32.9) % as determined by SDS-PAGE. 标签:His Tag 蛋白构建:A DNA sequence encoding the rhesus IL17A (XP_001106391.1) (Met 1 - Ala 155) and the mature form of rhesus IL17F (NP_001248216.1) (Arg 31 - Gln 163) linked by a ...
Studies of Th17 polarized mouse splenocytes also indicate the majority of IL-17 made is the IL-17A/F heterodimer. IL- 17F and IL-17A have been observed in tissue samples from various autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, psoriasis, inflammatory bowel disease, ...
IL17A/IL17F (Human) Recombinant Protein, None Tag Protein, P4799, high quality and rigorously validated in-house for Functional Study (Functional Study), SDS-PAGE (SDS-PAGE). IL17A/IL17F (Human) Recombinant Protein, P4799 is ready to ship.
Human IL-17A/F is a 40kDa glycoprotein which is secreted as a disulfide-linked heterodimer. IL-17A/F consists of two proteins of the IL-17 family, IL-17A and IL17F. Proteins of the 6 homodimeric IL17 family show a cysteine knot motif that contains two disulfide-bonds. Human IL17A is...
Human IL-17A/F is a 40 kDa glycoprotein which is secreted as a disulfide-linked heterodimer. IL-17A/F consists of two proteins, IL-17A and IL17F. Human IL17A is produced as a 155 a.a precursor that includes a 23 amino acids signal sequence and a 132 amino acid chain that includes ...
Both IL-17A and IL-17F are secreted by Th17 cells and other immune cells, including innate lymphoid cells [1]. Interleukin-17A is significantly more potent than IL-17F, whereas the IL-17A/IL-17F heterodimer has intermediate activity [2]. Both IL-17A and IL-17F use the IL-17 ...
Interleukin-17A (IL17A), a characteristic cytokine produced by the T helper 17 cells (Th17 cells), can form either a homodimer or a heterodimer with IL17F.It is produced not only by Th17 cells, but also by cytotoxic CD8+ T cells (Tc17 cells), ?d T cells, invariant natural killer T...
IL17A binds to the IL17RA homodimer, IL17RC homodimer, and/or IL17RA-IL17RC heterodimer [48] and activates intracellular ACT1 by changing its steric structure, subsequently transmitting the signal to IkB kinase alpha (IKKA)/IKKB [49]. In contrast, the downstream regulation of Akt and FOXO1 ...