4. Qiao, Y., Giannopoulou, E.G., Chan, C.H., Park, S.-H., Gong, S., Chen, J., Hu, X., Elemento, O., and Ivashkiv, L.B. (2013). Synergistic activation of inflamma- tory cytokine genes by interferon-g-induced chromatin remodeling and toll- like receptor signaling. Immunity...
[17].Hallett MA, Venmar KT, Fingleton B. Cytokine stimulation of epithelial cancer cells: the similar and divergent functions of IL-4 and IL-13. Cancer Res. 2012 Dec 15;72(24):6338-43. doi: 10.1158/0008-5472.CAN-12-3544. Epub 2012 Dec 7. PMID: 23222300; PMCID: PMC3531868....
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation,survival and gene expression.IL-4 is produced by mast cells,T cells,and bone marrow stromal cells.IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2...
2024年9月25日,相关研究以“A type 2 cytokine Fc–IL-4 revitalizes exhaustedCD8+T cells against cancer”为题在线发表在Nature,EPFL唐力教授、浙江大学药学院郭雨刚研究员以及耶鲁大学樊荣教授为论文的共同通讯作者。值得一提的是,由...
Background The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4 in a positive feedback loop. The cell that initially produces IL-4, thus inducing Th2 ...
Cytokine, 2015. 2. Junttila. Tuning the Cytokine Responses: An Update on Interleukin (IL)-4 and IL-13 Receptor Complexes. Frontiers in immunology, 2018. 3. Le Floc'h, A., et al. Dual blockade of IL-4 and IL-13 with dupilumab, an IL-4Rα antibody, is required to broadly inhibit ...
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into help...
IL4 is a pleiotropic cytokine produced by activated T cells. IL4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13,which may contribute to many overlapping functions of this cytokine and IL13. STAT6,a signal transducer and activator of transcription,has bee...
4. Qiao, Y., Giannopoulou, E.G., Chan, C.H., Park, S.-H., Gong, S., Chen, J., Hu, X., Elemento, O., and Ivashkiv, L.B. (2013). Synergistic activation of inflamma- tory cytokine genes by interferon-g-induced chromatin remodeling and toll- like receptor signaling.Immunity39...
重组大鼠白介素4(IL-4),Recombinant Rat Interleukin-4 (IL-4) Certificate of Analysis and Data Sheet Source: E.Coli Catalog No. CYT-385 Background :Interleukin-4 (IL4) has a compact, globular fold (similar to other cytokine