白细胞介素-1β(IL-1β或IL-1B)又称分解代谢素,是白细胞介素-1细胞因子家族的成员。IL-1β是由活化的巨噬细胞以前蛋白的形式产生的,并由半胱天冬酶-1 (CASP1/ICE)蛋白水解加工成活性形式。IL-1β是炎症反应的重要介质,参与多种细胞活动,包括细胞增殖、分化和凋亡。此外,IL-1β在中丨枢丨神丨经系统(...
Additionally, levels of ICC, IL-6, TNF-alpha, MCP-1, M1P-1 alpha and MIP-1 beta were significantly reduced and ICAM-1 and MUC5 A/C mRNA expression was attenuated. The viral load decreased significantly upon combined IL-1 alpha/IL-1 beta Ab treatment. Blocking the IL-1R1 provided ...
Cell cycle inhibition attenuates microglial proliferation and production of IL-1beta, M1P-lalpha, and NO after focal cerebral ischemia in the rat [J]. Glia, 2009, 57: 908-920.Zhang Q,Chen C,Lü J,et al.Cell cycle inhibition attenuates micro-glial proliferation and its associated IL-1β,...
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Mucosal Immunology Irf5 deficiency in myeloid cells prevents necrotizing enterocolitis by inhibiting M1 macrophage polarization Pubmed: 31086271 The role of amniotic fluid exosome, hypoxia inducible fator-1α, and inflammatory cytokine in cervical insufficiency pharmacological research Neuroprotection in non-...
IL-1 beta Protein, Human (E6K, His) 由大肠杆菌表达产生,由 269 个氨基酸 (M1-S269) 组成,其 N 末端带有His 标签。 Synonyms: Interleukin-1 beta; IL-1β; IL1F2; IL-1 beta; IL1B Species: Human Source: E. coli Biological Activity: 1.Measured by its binding ability in a functional ...
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Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways. Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1beta, IFN-beta, and IL-15 Pathways. J Immunol. 2015; 195:......
IL-18R beta /IL-1R7 Protein, Human (HEK293, Fc) 是一种重组蛋白,C 端带有 Fc 标签,由 358 个氨基酸 (M1-G357) 组成,在 HEK293 细胞中表达。 Synonyms: Interleukin-18 receptor accessory protein; CDw218b; IL-1R7; IL-18R-beta; CD218b Species: Human Source: HEK293 Biological Activity: ...
摘要: Oncogene is one of the world's leading cancer journals. It is published weekly and covers all aspects of the structure and function of Oncogenes. Oncogene also publishes 8 Reviews issues a year, on a broad range of topics.关键词: Isoenzymes Peptides Protein Kinase C Receptors, ...