四、参考文献: Inhaled siRNA nanoparticles targeting IL11 inhibit lung fibrosis and improve pulmonary function post-bleomycin challenge.PMID:35731866 Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease.PMID:36470928 IL11 activates the placental infla...
Inhaled siRNA nanoparticles targeting IL11 inhibit lung fibrosis and improve pulmonary function post-bleomycin challenge. Authors - Xin Bai KD Validated View Article human,mouse IHC Life Sci The effect of hepatic stellate cell derived-IL-11 on hepatocyte injury in hepatic fibrosis Authors - Ling-Feng...
由于肿瘤转移是患者死亡的主要原因,作者将重点放在对侵袭和迁移至关重要的基因上。为有效敲除这50个基因,利用内切核糖核酸酶制备的siRNA文库,检测了在常氧或缺氧条件下,每个基因对MDA-MB-231细胞侵袭的影响。通过结合生长在I型胶原上的细...
Transient IL-11-KO Tie-GFP mice were generated as follow; For in vivo RNAi studies, IL-11 siRNA (ID AM16832, Ambion) or non-targeting control siRNA (Cat#: 4404021, Ambion) were reconstituted (5 µg/µl) in nuclease-free water and administered to the lungs to 24 weeks old mice ...
CAS号: 英文名: IL-11Rα siRNA (m) 英文别名: IL-11Rα siRNA (m) 中文名: 中文别名: CBNumber: CB09720675 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 IL-11Rα siRNA (m)化学性质 安全信息...
Lastly, targeted delivery of ALKBH5 or IL-11 receptor 伪 (IL11RA1) siRNA to monocytes/macrophages attenuates MMT and cardiac fibrosis under hypertensive stress. Our results thus suggest that the ALKBH5/IL-11/IL11RA1/MMT axis alters cardiac macrophage and contributes to hypertensive cardiac ...
Transfection of Lentivirus vector or siRNA interference. Lentivirus vector expressing IL-11(LV-IL-11) and negative control were purchased from Realgene Company (Nanjing, Jiangsu). Lentivirus vector with shRNA targeting IL-11 receptor ( LV- IL-11RαRNAi target 5′-GGACCATACCAAAGGAGAT...
Specifically, siRNA-mediated knockdown of IL-11 sensitized the cells to paclitaxel-induced cell death, while anti-IL-11 antibody added to culture medium increased doxorubicin-induced apoptosis. Indeed higher IL-11 expression was associated with reduced progression-free and overall survival in a cohort...
公司致力于为生物科学领域内的客户提供高质量的产品和优质的服务。公司主要业务有三大类:一、生化试剂(液体加粉剂); 二、丰富的细胞资源库; 三、销售基因、载体、菌株、细胞、眼病毒、慢病毒、siRNA/shRNA第生物资源产品。 我司具有资深的编辑团队,专业的科研技术团队,有严格的质量把控,提供一站式贴心服务。我们...
As anticipated, siRNA-mediated knockdown of TWF1 inhibited IL-11 mRNA and protein expression in MDA-MB-231 cells, similar to the effect of miR-30c on IL-11 (Fig. 5e,f). These data suggest that IL-11 is an important target of TWF1 in the miR- 30c signalling pathway, which ...