IL-1, IL-18, and IL-33 families of cytokines. William P Arend,Gaby Palmer,Cem Gabay. Immunological Reviews . 2008Arend WP, Palmer G, Gabay C: IL-1, IL-18, and IL-33 families of cytokines. Immunol Rev 2008, 223:20-38.Arend WP,Palmer G,Gabay C.IL-1,IL-18,and IL-33 families...
但是,在存在IL-3的情况下,IL-18直接激活基底球并诱导IL-4 / IL-13和组胺,而没有FceRI交联,即IL-18是一种过敏原。它可以独立于IgE诱导过敏反应,此外,IL-18刺激NKT细胞而无抗原刺激,诱导IL-4 / IL-13产生,并且在体内施用IL-18时也如此。单独诱导IgE产生。 著录项 来源 《臨床免疫·アレルギー科》 ...
大多数IL-1家族细胞因子具有促炎活性(IL-1α,IL-1β,IL-18,IL-33,IL-36α,β,γ),而...
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Arend, W. P., Palmer, G. & Gabay, C. IL-1, IL-18, and IL-33 families of cytokines.Immunol. Rev.223, 20–38 (2008). ArticleCASPubMedGoogle Scholar Netea, M. G.et al. Differential requirement for the activation of the inflammasome for processing and release of IL-1β in monocyte...
Based on the length of the N-term pro-pieces, the members of IL-1 family can be classified into 3 subfamilies: IL-1 subfamily (IL-1α, IL-1β and IL-33, IL-1Ra), IL-18 subfamily (IL-18 and IL-37), and IL-36 subfamily (IL-36α, IL-36β, IL-36γ, and IL-38). ...
NLRs act in tandem with other cytosolic and transmembrane PRRs to sense intracellular pathogens/pathogenic ligands, thereby activating the downstream inflammatory pathways ultimately leading to release of pro-inflammatory cytokines involved in inflammatory responses8. The inflammatory responses in mammals are ...
Both experimentally induced or naturally occurring mastitis results in an increase in the somatic cell count (SCC) and levels of produced cytokines (interleukin (IL) IL-1, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, and IL-12) in milk [18]. Similarly, also biochemical analysis of milk...
英文名称:Recombinant Interleukin 18 Receptor 1 (IL18R1) 分子式:电询 纯度:99 % 产地:进口/国产 品牌:钰博生物 包装规格:50ug 别名:电询 白介素18受体1(IL18R1)重组蛋白 FOR IN VITRO AND RESEARCH USE ONLY, NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES!
白细胞介素1(IL-1) 蛋白家族包含经典成员IL-1α、IL-1β和IL-1ra, 以及IL-18、IL-33和IL-1F5-10。IL-1α和IL-1β结合于相同的细胞表面受体, 共享生物学功能。除了皮肤角质形成细胞、 一些上皮细胞以及中枢的某些细胞之外, 健康小鼠未刺激的细胞不产生IL-1。 但是, 作为对物质、 感染或微生物内毒素的...