IL-1beta promotes the age-associated decline of beta cell functionCell biologyCellular physiologyPhysiologyAging is the prime risk factor for the development of type 2 diabetes. We investigated the role of the interleukin-1 (IL-1) system on insulin secretion in aged mice. During aging, ...
a血管平滑肌细胞表达炎症因子IL-1α和β的基因,并以自分泌的形式分泌IL-1来调控细胞功能 Blood vessel smooth muscle cell expression inflammation factor IL-1α and beta the gene, and by secretes IL-1 from the secretion form to regulate the cell function[translate]...
Warning: Invalid argument supplied for foreach() in /home/prospec/public_html/cart/Smarty-2.5.0/plugins/function.interpro.php on line 30 Gene: Name:Il1b Protein synonyms/aliases: Interleukin-1 beta precursor (IL-1 beta). Protein Family: Belongs to the IL-1 family. ...
TRAIL R4 retains a C-terminal element containing one third of aconsensus death domain motif. Transient overexpression of TRAIL R4 in cells normally sensitive to TRAIL-mediated killing confers completeprotection, suggesting that one function of TRAIL R4 may be inhibition of TRAIL cytotoxicity. 展开 ...
Toll-like receptor 2, 3, and 4 expression and function in human airway smooth muscle Host defense against microbial pathogens is elicited through the innate immune system by means of Toll-like receptors (TLRs). Airway smooth muscle cells (A... M Sukkar,S Xie,N Khorasani,... - 《Journal ...
Long Name Interleukin 1 beta Entrez Gene IDs 3553 (Human); 16176 (Mouse); 24494 (Rat); 397122 (Porcine); 403974 (Canine); 100034237 (Equine); 100135556 (Guinea Pig) Alternate Names catabolin; IL1 beta; IL-1 beta; IL-1; IL1B; IL-1b; IL1-BETA; IL-1F2; IL1F2IL-1 beta; inte...
Interleukin-1 is a potent pro inflammatory agent, has a direct influence on human thyroid cell function, and modulates cell growth in differentiated thyroid carcinoma cell lines. To evaluate whether a polymorphism on the IL-1beta gene has an influence on the incidence of thyroid disorders, we an...
Transient overexpression of TRAIL R4 in cells normally sensitive to TRAIL-mediated killing confers completeprotection, suggesting that one function of TRAIL R4 may be inhibition of TRAIL cytotoxicity.Ig TypeRabbit IgG
1-Function 2-Post-translational modifications 3-Sequence similarities 4-Tissue specificity 5-Cellular localization 6-Alternative names 7-Database links 8-Target type 9-Primary research area 10-Other research areas 11-Molecular weight The precursor is cytosolic. In response to inflammasome-activating sign...
用途:Insulin, recombinant human (rHu) is identical in function and structure to the native human sequence. A hormone consisting of two polypeptide chains, rHu Insulin′s A-chain (21 amino acids) and B-chain (30 amino acids) are covalently linked by disulfide bonds between cysteine residues. ...