In this article, we have shown that IL-1 beta is a key molecule that can orchestrate both Toll-like receptor and muscarinic receptor pathways, and that antagonizing the function of IL-1 beta has a promising future as a potential drug target for asthma treatment. IL-1 beta can activate NF...
Entrez Gene IDs 3553 (Human); 16176 (Mouse); 24494 (Rat); 397122 (Porcine); 403974 (Canine); 100034237 (Equine); 100135556 (Guinea Pig) Alternate Names catabolin; IL1 beta; IL-1 beta; IL-1; IL1B; IL-1b; IL1-BETA; IL-1F2; IL1F2IL-1 beta; interleukin 1, beta; interleukin-...
Recombinant Monoclonal. View Human IL-1 beta/IL-1F2 Alexa Fluor® 750-conjugated Antibody (IC8406S) validated in Human & Intracellular Staining by Flow Cytometry from R&D Systems.
用途:Insulin, recombinant human (rHu) is identical in function and structure to the native human sequence. A hormone consisting of two polypeptide chains, rHu Insulin′s A-chain (21 amino acids) and B-chain (30 amino acids) are covalently linked by disulfide bonds between cysteine residues. ...
Transient overexpression of TRAIL R4 in cells normally sensitive to TRAIL-mediated killing confers completeprotection, suggesting that one function of TRAIL R4 may be inhibition of TRAIL cytotoxicity.Ig TypeRabbit IgG
Alternate Names catabolin; IL1 beta; IL-1 beta; IL-1; IL1B; IL-1b; IL1-BETA; IL-1F2; IL1F2IL-1 beta; interleukin 1, beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta Product Datasheets Product Datasheet ...
Long non-coding RNA cancer susceptibility candidate 2 regulates the function of human fibroblast-like synoviocytes via the microRNA-18a-5p/B-cell translocation gene 3 signaling axis in rheumatoid arthritis. Bioengineered 13:3240-3250 (2022). [3]Wang S et al. TRIM27 suppresses inflammation injuries...
It is now well accepted that the brain and the immune system are intimately linked and that cytokines, small proteins secreted by cells of the immune system, exert diverse effects on CNS function. Of particular importance in this regard is the proinflammatory cytokine interleukin-1 beta (IL-1β...
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. MyD88, originally isolated as a myeloid differentiation primary response gene, is shown to act as an adaptor in interleukin-1 (IL-1) signaling by interacti... ADACHI,O. - 《Immunity》 被引量:...
Function: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being ...