两个受体膜内部分最主要的区别在于TNFR1上面有一个死亡区域，TNFR2上没有，这一死亡区域是一段约70个氨基酸的序列，这一区域对TNF-α启动的细胞凋亡是必须的。与Fas蛋白的死亡区域相似，这一细胞内的区域是种附属信号蛋白的结合位点，这些蛋白包括Fas相关死亡区段结合蛋白（FADD），TNFR-1相关死亡区段...
a血管平滑肌细胞表达炎症因子IL-1α和β的基因,并以自分泌的形式分泌IL-1来调控细胞功能 Blood vessel smooth muscle cell expression inflammation factor IL-1α and beta the gene, and by secretes IL-1 from the secretion form to regulate the cell function[translate]...
分子别名(Synonyms) IL23 alpha; IL12 β; IL23 alpha&IL12 beta ; 表达区间及表达系统(Source) Mouse IL-23 alpha&IL-12 beta Protein is expressed from HEK293 with His tag at the N-Terminus. It contains Val22-Ala196(IL-23 alpha)&Met23-Ser335(IL-12 beta).[Accession | Q9EQ14-1(...
The protein has a predicted MW of 19.5 (Cynomolgus IL23 alpha)&35.8 (Mouse IL12 beta) kDa. Due to glycosylation, the protein migrates to 22 (Cynomolgus IL23 alpha)&40-50 (Mouse IL12 beta) kDa based on Tris-Bis PAGE result.
The protein has a predicted MW of 21.7 kDa (Human IL-23 alpha) & 35.8 kDa (Mouse IL-12 beta). Due to glycosylation, the protein migrates to 22 kDa (Human IL-23 alpha) & 45-60 kDa (Mouse IL-12 beta) based on SDS-PAGE result.内...
The protein has a predicted MW of 52.07 kDa(IL-22R alpha 1)&48.85 kDa(IL-10R beta). Due to glycosylation, the protein migrates to 68-75 kDa based on SDS-PAGE result.内毒素(Endotoxin) Less than 1EU per μg by the LAL method.纯度...