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IL-l β is the predominant free extracellular form, whereas most IL-l α is membrane-bound. IL-l α and IL-1 β are synthesized as precursor molecules, each with an approximate mol wt of 31 kDa. Processing of IL-l α and IL-1 β to mature forms of 17 kDa requires specific ...
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All animals were provided with a standard diet and housed in pathogen-free cages at constant temperature and humidity. The circadian rhythm was maintained at 12 hours. The Southern Medical University Animal Care and Use Committee approved all procedures involving mice. All animal procedures involving ...
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Marquina et al., “Inhibition of B cell death causes the development of an IgA nephropathy in (New Zealand White x C57BL/6)F1-bcl-2 transgenic mice,” J. Immunol., 172(11): 7177-7185 (2004). Martin, A.C.R., “Protein Sequence and Structure Analysis of Antibody Variable Domains,”...
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“Linear DNA” denotes non-circular DNA molecules having free 5′ and 3′ ends. Linear DNA can be prepared from closed circular DNA molecules, such as plasmids, by enzymatic digestion or physical disruption. “Complementary DNA (cDNA)” is a single-stranded DNA molecule that is formed from an...