Notably, the opposite (protective) allele IL1RN*2 has been previously associated with higher IL-1Ra and lower IL-1β release60. In conclusion, our study shows that the elucidation of pathogenic, inflammasome-dependent mechanisms at the molecular level may help the development of novel strategies ...
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The development of monocytes in huNOG-EXL is in accordance with the requirement of GM-CSF for monocytes/macrophages differentiation [29]. PaPtahtohgoegnesn2s021091,98,,83,3x FOR PEER REVIEW 4 4oof f1176 A P=0.002 NS 100 B P=0.02 100 NS C P=0.002 NS 100 80 80 80 60 60 60 40 ...