Objective:To detect the expression and changes of IL-1β in the rats heart transplantation, and assess the effect IL-1β on the acute rejection in rats heart transplantation. Method:A simplified heterotopic heart transplantation model, inbred SD and wistar rats were used as donors and recipients...
Acute cholecystitis is inflammation of the gallbladder, and a delayed diagnosis of this condition increases the incidence of patient complications and mortality. Although proinflammatory cytokines are reported to be critical mediators in hepatobiliary disease, little is known regarding the biliary cytokine ...
PBMC and acute skin lesions of patients with atopic dermatitis (AD) are characterized by increased IL-4 and IL-13, but decreased IFN-gamma production. This bias toward an increased Th2 cytokine profile may contribute to the elevated IgE levels and acute skin inflammation seen in AD. In this...
Association between interleukin-10 (IL-10) gene promoter polymorphisms and outcome in acetaminophen induced acute liver failure requiring admission to a liver ... N Jackson,S Cookson,W Bernal,... - 《Critical Care》 被引量: 0发表: 2000年 Reduced monocyte HLA‐DR expression: A novel biomarker...
Acute myeloid leukemia (AML) is characterised by defects in the regulation of hematopoietic cell survival, differentiation and proliferation. IL-3 and GM-CSF exert potent survival and proliferative effects on a range of myeloid progenitor cells. Previously we have identified a novel cytoplasmic motif ...
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Should we target the virus, the cell or the disease? Volume 24, issue 3, Mai-Juin 2020 PDF Print Save to My profile Export Citation for this article E-mail link to t...
However, the plasma levels of IL-37 in patients with acute coronary syndrome (ACS, including unstable angina pectoris and acute myocardial infarction) have yet to be investigated.Plasma IL-37, IL-18, and IL-18BP levels were measured in 50 patients with stable angina pectoris (SAP), 75 ...
IL-18 (known as an interferon-gamma (IFN-γ) inducing factor), and other inflammatory cytokines have important roles in lipopolysaccharide (LPS)-induced acute kidney injury (AKI). We investigated the effect of inflammatory cytokines and Toll-like receptor 4 (TLR4) expression, an event that is ...
Uncontrolled hapatic inflammatory response is regarded as the primary pathological mechanism of acute liver failure and impairs the regeneration of hepatocytes and stem cell grafts. Interleukin-1 plays a key role for activating immune and inflammatory response. Recently, siRNA has made quite a few prog...