et al. Self-renewal of CD133hi cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer. Nat. Commun. 7:10442 doi: 10.1038/ncomms10442 (2016). This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party...
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On the other hand, the synergistic rise of IL-17 and IL-22 creates a niche that is suited for the healing of limb scar wounds, which eliminates the potential for renewal of the scar. The potential for healing that cinnamaldehyde possesses in mouse skin wounds that have been infected with ...
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to ...
Wnt signaling has been shown to be important for the self-renewal and function of Lgr5+ ISCs (Li et al., 2018; Mah et al., 2016; Yin et al., 2014). Therefore, the initial activation of Wnt signaling in stem cells may be involved in IL-17RA-mediated induction of Atoh1 and ...
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Under a Creative Commons license open accessHighlights Summary Inflammatory responses are known to facilitate tissue recovery following injury. However, the precise mechanisms that enhance lung alveolar regeneration remain unclear. Here, using an organoid-based screening assay, we find that interleukin-1 ...
The European Medicines Agency’s human medicines committee again decided not to recommend the renewal of the conditional marketing authorization for PTC Therapeutics’ Duchenne muscular dystrophy drug Translarna. The treatment has gone through multiple reviews by the committee. Friday’s decision is the ...
Western blotting shows p63, loricrin, KRT10, and TGase1 modifications upon treatment with LUT-7G (j) STAT3 phosphorylation.41 Phosphorylation in serine 727 (p-S727) has been described, but only p-Y705 is absolutely required for STAT3-mediated self-renewal in epithelial stem cells and ...
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