Wilmette, IL地区的Illinois Bone & Joint Institute员工评价点评此公司 职位名称 不限 地点 Wilmette, IL4 条点评 按类别评分 3.3工作-生活平衡 3.3薪资与福利 3.1职位安全与晋升 3.0管理方式 3.2企业文化 搜索评价 搜索 排序方式 评分时间 语言 已找到符合搜索的4条评价查看165 条评论...
本研究的结果有助于更好理解DNA甲基化水平的机制,IL-19干预有望成为骨代谢相关疾病一个新的治疗和预防手段。 科研团队的另一篇文章于2023年11月,发表在《Bone & Joint Research》杂志(JCR 1区,IF:4.73),题为“Interleukin-19 promo...
In fact, elevated intracel- lular Ca2+ triggers IL-1α secretion from bone marrow-derived cells.132,137,138 An increase in the Ca2+ concentration was shown to be sufficient for inflammasome-independent IL-1α processing by calpain and its subsequent secretion.137 Interest- ingly, increased ...
However, we found that two genotypes (1-2/1-2 and 2-1/2-2) show a trend toward association with susceptibility to disease.关键词: Genetic Predisposition to Disease IL1 IL1RN Knee Osteoarthritis DOI: 10.1007/s00296-011-1946-3 被引量: 42 ...
The objective of this study was to determine whether a biphasic scaffold loaded with a combination of a chemokine and bone marrow concentrate (BMC) could improve tissue regeneration in knee articular cartilage of beagles with cylindrical osteochondral defects. For this investigation, an osteochondral def...
Define Manderil. Manderil synonyms, Manderil pronunciation, Manderil translation, English dictionary definition of Manderil. n. 1. A mandrel. Webster's Revised Unabridged Dictionary, published 1913 by G. & C. Merriam Co
There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced ...
Even if Ps and PsA share several genetic risk loci, disease-specific mutations have also been researched in the attempt to better understand the differences between the skin and the joint involvement. For instance, among the HLA-genes, some alleles of the HLA-B (B*08, B*27, B*38, and ...
IL-23 is produced by activated myeloid cells, whereas IL-17 is predominantly produced by T cells and innate lymphoid cells. Several lines of evidence support a role for the IL-23–IL-17 pathway in the pathogenesis of psoriatic arthritis (PsA) and ankylosing spondylitis (AS). Bone changes tha...
We conducted a study testing the hypothesis that IL-18 predicts disease activity in patients with rheumatoid arthritis (RA), as measured by the number of swollen joints (40 joint counts), DAS28, the sedimentation rate and bone erosion. The study consisted of 57 patients with RA and 20 contro...