中文名称:IL-1 Alpha白介素1α/IL-1α抗体现货 英文名称:IL-1 Alpha 别名:interleukin-1 alpha; Hematopoietin 1; IL 1 alpha; IL1 alpha; IL 1; IL 1A; Il-1a; IL1; IL1A; IL1F1; ilia; Interleukin 1 alpha; Interleukin 1 alpha precursor; Interleukin1 alpha; Preinterleukin 1 alpha; Pro...
Recombinant Interleukin 11 Receptor Alpha (IL11Ra) [ PROPERTIES ]Source: Prokaryotic expressionHost: E.coliResidues: Trp59~Pro220Tags: N-terminal His TagSubcellular Location: MembranePurity: > 90%Traits: Freeze-dried powderBuffer formulation: 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, ...
[9]Emery P, Fleischmann RM, Moreland LW, et al. Golimumab, a human anti-tumor necrosis factor alpha monoclonal antibody, injected subcutaneously every four weeks in methotrexate-naive patients with active rheumatoid arthritis: twenty-four-week resul...
IL-1(IL-1 alpha、IL-1 beta) 几乎影响所有细胞和器官,并且是自身炎症、自身免疫、感染性和退行性疾病的主要致病介质。 CD121a/IL1R1, CD121b/IL1R2 CD4+细胞 共刺激 B细胞 成熟&增殖 NK细胞 活化 巨噬细胞、内皮细胞、其他细胞 参与炎症反应,少量引起急性期反应,大量引起发热 IL-4 除了在介导炎症性过...
英文名字 Human IL-1 alpha protein 中文名称 【IL1A】重组人白介素1 alpha 货号PRP100048背景资料: 白细胞介素-1,简称白介素1 (IL-1),是一种细胞因子,属于白细胞介素的一种。白细胞介素(interleukin,IL),简称白介素,是指在白细胞或免疫细胞间相互作用的淋巴因子。白细胞介素在传递信息,激活与调节免疫...
6. B. C. Betts, E. T. St Angelo, M. Kennedy, J. W. Young, Anti-IL6-receptor-alpha (tocilizumab) does not inhibit human monocyte-derived dendritic cell maturation or alloreactive T-cell responses. Blood 118, 5340-534...
Interleukin-1 beta (IL-1β) is a pro inflammatory cytokine, which is secreted by immune cells to trigger inflammation and this has been found profoundly in the lesions caused by Leishmania pathogens.IL-1 is a name that designates two pleiotropic cytokines, IL-1 alpha (IL-1F1) and IL-1 ...
stimulatory effect of IL1-beta on the production of soluble and intracellular forms of IL-1RN. The regulated expression of IL-1RN in various cell types has been shown to be influenced by cytokines. In synovial fibroblasts, IL-1, TNF-alpha, or PDGF markedly enhances the synthesis of IL-1...
IL-6 发挥促炎功能并受到可溶性 IL-6R (sIL-6R) 和gp130受体参与的跨膜信号转导调控。sIL-6R是IL-1beta和TNF-alpha活化的产物。这两种促炎细胞因子活化ADAM10和ADAM17脱落酶水解IL-6R。 与其他可溶性受体(例如IL-1RA和IL-18BP)不同,sIL-6R 不是 IL-6 的抑制剂。相反,它通过与IL-6和 gp130 形成复合...
靶点别名:IL23A (interleukin 23 subunit alpha), IL12B (interleukin 12B) 1.IL23蛋白的种属特异性表达 用ELISA方法检测野生型小鼠(+/+)和纯合B-hIL23A/hIL12B小鼠(H/H)中IL23A的表达情况,结果显示小鼠IL23A仅在野生型小鼠WT (+/+)中表达,而人IL-23仅在纯合B-hIL23A/hIL12B 小鼠(H/H)中表达。