IL-23/IL-17 axis in IBD. Sarra A,Pallone F,Macdonald T T, et al. Inflammatory Bowel Diseases . 2009Sarra, M., F. Pallone, T. T. Macdonald, and G. Monteleone. 2010. IL-23/IL-17 axis in IBD. Inflamm. Bowel. Dis. 16: 1808-1813....
AS是一种脊柱多发性附着点炎,IL-23抑制剂对于AS无效。但有证据表明IL-23抑制剂对PsA的外周附着点炎有效,并初步提出其在中轴型PSA中受益,因此受到质疑。其中的关键是脊柱炎是否可以产生独立于IL-23的终末IL17A,但外周附着点炎很大程度上依赖IL23驱动...
This article reviews what is known about the role of the IL 23–IL 17 immune pathway at different stages in the development and progression of chronic immune-mediated inflammatory diseases, in particular rheumatoid arthritis and spondyloarthritis. The au
关键字:反流性食管炎;IL23;IL17 ABSTRACT:ObjectiveTodetecttheexpressioof interleukin17(IL17)andinterleukin23(IL23)in esophagealtissuesofratswithrefluxesophagitis(RE)and exploretheroleofIL23/IL17axisinthepathogenesisof RE.MethodsThirtySDratswererandomlypidedinto3groups, ...
Conclusion Emodin can protect against VMC by inhibiting IL-23/IL-17 inflammatory axis, Th17 cell proliferation and viral replication in mice. Key words: emodin; viral myocarditis; interleukin-23; interleukin-17; Th17 cells 收稿日期:2013-11-24 基金项目:国家自然科学基金(81172055) Supported by ...
IL-23–responsive innate lymphoid cells are increased in inflammatory bowel disease Results of experimental and genetic studies have highlighted the role of the IL-23/IL-17 axis in the pathogenesis of inflammatory bowel disease (IBD). IL-2... A Geremia,CV Arancibia-Carcamo,MPP Fleming,... ...
The TNF/IL‐23/IL‐17 axis—Head‐to‐head trials comparing different biologics in psoriasis treatment. Scandinavian Journal of Immunology, 92(4), p.e12946. Torres, T., Puig, L., Vender, R., Lynde, C., Piaserico, S., Carrascosa, J.M., Gisondi, P., Daudén, E., Conrad, C., ...
IL-23/IL-17轴因子在初诊Graves病患者治疗前后的变化 Objective To detect the expression level of interleukin-17 (IL-17)/interleukin-23 (IL-23) axis in peripheral blood of patients with Graves disease (GD) bef... 杨铭,潘天荣,钟兴 - 《安徽医科大学学报》 被引量: 0发表: 2017年 肠愈灌肠方治...
TAO 患者的IL-17、IL-23水平与临床活动性评分（CAS）均呈正相关（r =0.6305和0.6892，均P =0.000）。结论 IL-17、IL-23在TAO 患者外周血中均高表达。关键词： 甲状腺相关眼病；白介素17；白介素23；IL-23/IL-17炎症轴 中图分类号： R446.62 文献标识码： A Expression and clinical ...
The discovery that the IL-23-IL-17 immune pathway is involved in many models of autoimmune disease has changed the concept of the role of T-helper cell subsets in the development of autoimmunity. In addition to TH17 cells, IL-17 is also produced by other T cell subsets and innate immune...