E2F1 overexpression has a cis-effect on the regulation of IKK beta, NF kappa B and SURVIVIN, but has a trans-effect on IKK alpha regulation. Regulation of the expression of SURVIVIN by E2F1 in ECA109 cells may be conducted through the activation of IKK beta, which subsequently activates the...
摘要: NE-kappa B-inducing kinase (NIK; also known as MAP3K14) is a central regulator of non-canonical NF-kappa B signaling in response to stimulation of TNF receptor superfamily members,... 查看全部>>关键词: NE-kappa B-inducing kinase NIK Lymphotoxin-beta receptor LT beta R Inflammation...
别名:IKKB, phosphorylated (T180) (IKBKB, IKKB, Inhibitor of nuclear factor kappa-B kinase subunit beta, I-kappa-B kinase 2, Nuclear factor NF-kappa-B inhibitor kinase beta) (MaxLight 750) CAS番号: 分子式: 分子量:0 EINECS: Mol File:Mol File ...
This study demonstrates the efficacy of Delta C-IKK gamma as a repressor of IKK signaling and NF-kappa B activation and suggests a potential gene therapy approach to limit chronic inflammation due to chemokine hyperactivation. 展开 关键词: AIDS/HIV NL4-3 IIIB T lymphocyte signal transduction JAK...
IKKB, phosphorylated (T180) (IKBKB, IKKB, Inhibitor of nuclear factor kappa-B kinase subunit beta, I-kappa-B kinase 2, Nuclear factor NF-kappa-B inhibitor kinase beta) (MaxLight 750)化学性质安全信息IKKB, phosphorylated (T180) (IKBKB, IKKB, Inhibitor of nuclear factor kappa-B kinase ...
NLK NF-κB TNFα IKKβ TAK1 1. Introduction Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor complexes that regulate cell survival and proliferation. Dysregulation of NF-κB leads to chronic inflammatory diseases and development of cancer...
英文名称:IKKB phosphorylated Inhibitor Of Nuclear Factor kappa B Kinase beta Subunit I kappa B kinase beta IkBKB B kappa Kinase 2 Nuclear Factor NF Inhibitor IKKBIKKB phosphorylated Inhibitor Of Nuclear Factor,中文名称:核因子kappa B激酶β亚基磷酸化抑制
The transcription factor NF-kappa B plays an important role in both physiological and pathological events in the central nervous system. Nevertheless, the mechanisms of NF-kappa B-mediated regulation of gene expression, and the signaling molecules participating in the NF-kappa B pathway in the centr...
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A feedforward loop of NLRC5 (de)ubiquitination keeps IKK–NF-κB in check Many receptors signal via adaptors to the IKK-NF-κB axis, transducing extracellular cues to transcriptional regulation. In this issue, Meng et al. (2015. ... Y Hu - 《Journal of Cell Biology》 被引量: 1发表: ...