MRT67307 (IKKε/TBK1 Inhibitor II) inhibitsIKKεandTBK1with IC50 values of 160 nM and 19 nM at 0.1 mM ATP in vitro, but does not inhibit IKKα or IKKβ even at 10 μM. MRT67307 also is a highly potentULK1andULK2inhibitor with IC50s of 45 and 38 nM, respectively. MRT67307 can ...
2.4 shRNA对HUVECs中IKKα蛋白表达的影响 Western blot检测结果显示, 以β-actin为内参照, IKKα在正常HUVECs中呈基础表达(图4). 高糖培养48 h后, HUVECs中IKKα蛋白表达量上升, 与对照组相比具有显著性差异(P<0.05); 而转入了IKKα shRNA后用高糖培养基培养48 h, RNAi 1, 2, 3组HUVECs中IKKα蛋白表...
IKK-FCK1 7.5HP 190/380V 50HZ 2P S/N:45299030 IK-FBKX 3.7KW 380V 50HZ 4P S/N:20518724 PSH01 380V 75KW 4 D25M () :S75245000 TIKK-FCKBS8 15KW 380V 52/69HZ 4P S/N:40234183 TIKK-FCK21 15KW 400V 52HZ 6P S/N:40234181 IKK-FCKLAW21 7.5KW 380V 50HZ IKK-FCKLAW21 5.5KW 380V...
160, 71–79 (2019). Article CAS PubMed Google Scholar Lenz, G. et al. t-Darpp activates IGF-1R signaling to regulate glucose metabolism in trastuzumab-resistant breast cancer cells. Clin. Cancer Res. 24, 1216–1226 (2017). Article PubMed PubMed Central Google Scholar Zhu, S., Belkh...
VAHLE 0600084/00 KBHS4/160-4000HSCVAHLE 0194777/00 SA-SWNT7/40-1HS28-60HMS AB7000-C suco 压力传感器 0180-45803-1-042VAHLE 0180181/00 LSVG10/140-1000HSVAHLE 0175489/00 ES-UE35AE-L-Bmahle 77687478 852 471VAHLE 0105670/00 IS-VDO35-PE-K-M16X40EKK 18.010-Cu57B parker D1VW001KNJW...
Based on its anti-inflammatory properties in VSMCs, LCY-2-CHO has therapeutic potential in atherosclerosis [160]. Other drugs Human ß-defensin 3 (hBD3) is a cardio-protective natural peptide found in mucous membranes, cells of the epithelium, and cells of the endothelium. In ApoE−/...
For example, the H-TSPCs were spindle- or cobble-stone-shaped, while the S-TSPCs were round and flattened (Figures 1A, 1B, and S1). Through flow cytometric analysis, we found no difference in the expression of stem cell-related surface markers on the S-TSPCs and H-TSPCs (Figure S2...
This study first demonstrated that NLRC3 deficiency promoted hypoxia-stimulated PASMCs proliferation, Human umbilical vein endothelial cells (HUVECs) apoptosis, migration and inflammation through IKK/NF-κB p65/HIF-1α pathway in vitro and in vivo, further promoted vascular remodeling and PH progression...
25cm/s Centrifugal Force 13KN Certification CE, ISO 9001:2000 Condition New Product Name Impacting Rammer Engine Honda Gx160 5.5HP Power 5.5HP Plate Size 300*310mm Transport Package Hob with Carton Specification CE Trademark KZW Origin Ningbo, China ...
target: sgm.modules.encoders.modules.FrozenOpenCLIPEmbedder2 params: arch: ViT-bigG-14 version: laion2b_s39b_b160k freeze: True layer: penultimate always_return_pooled: True legacy: False # vector cond - is_trainable: False input_key: original_size_as_tuple ...