et al. Specificity and affinity of human Fcγ receptors and their polymorphic variants for human IgG subclasses. Blood 113, 3716–3725 (2009). Article PubMed CAS Google Scholar Sondermann, P., Huber, R., Oosthuizen, V. & Jacob, U. The 3.2-A crystal structure of the human IgG1 Fc ...
Disease associations with isolated elevations of each of the four IgG subclasses[l]. Semin Arthritis Rheum, 2017, 47(2): 276-280.D0I: 10.1016/j.semarthrit.2017.03.021. [5] Rispens T, Huijbers MG. The unique properties of IgG4 and its roles in health and disease[1]. Nat Rev Immunol,...
immunoglobulin G subclassespancreatitistubulointerstitial nephritisIn summary, we have described here a patient with immune complex-mediated TIN in association with AIP. The renal lesion is strongly suspected to be induced by IgG4 or immune complexes containing IgG4. This case appeared of value in ...
1. Bruhns, P.; Iannascoli, B.; England, P.; Mancardi, D. A.; Fernandez, N.; Jorieux, S.; Daëron, M., Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses. Blood 2009...
Subclasses IgG1, IgG2, IgG3, and IgG4 are differentiated on the basis of the size of the hinge region, position of interchain disulfide bonds, and molecular weight. The subclasses also differ in their ability to activate complement.
Potential of murine IgG1 and human IgG4 to inhibit the classical complement and Fcγ receptor activation pathways[J].Front Immunol, 2018,9:958. DOI: 10.3389/fimmu.2018.00958 . 返回引文位置Google Scholar 百度学术 万方数据 [7] Vidarsson G , Dekkers G , Rispens T .IgG subclasses and allo...
One major interesting finding was that RTX specifically reduced IgG4 levels, while the other IgG subclasses remained stable. This has led to the hypothesis that short lived plasma cells producing IgG4 are involved in the disease [[84],[120]]. Conclusions and future perspectives Over the last ...
18 compared the infiltration of mucosal IgG4+ plasma cells in intestinal tissues of patients with IBD and patients with autoimmune pancreatitis (AIP). This study demonstrated that patients with IBD had higher intestinal mucosal IgG4 counts than patients with AIP. Another study by Raina et al.19 ...
Distribution: intra- and extravascular Function: secondary response Page contents The role of IgG in the immune response IgG subclasses The role of IgG in the immune response IgG is the major immunoglobulin in blood, lymph fluid, cerebrospinal fluid and p...
IgG4 is the least abundant of the human IgG subclasses and for decades was only a curiosity amongst allergists, who spent several years debating its role i... SH Lou,LK James - 《European Journal of Immunology》 被引量: 0发表: 2020年 Hyper-Immunoglobulin E (IgE) Syndrome: A Diagnostic ...