Four had kappa and two had lambda light chain expression. Three cases expressed CD56. Two patients had a complex karyotype. In conclusion, the frequency of IgG4 myeloma correlates with the normal distribution of IgG4 isoform. The patients with IgG4 myeloma appear to have a high rate of ...
Total 402 patients of PCPD were included (10.9% of MGUS/SMM and 89.1% of multiple myeloma). The combination of SPE+rSFLC (ratio of kappa/lambda light chain) and SPE+IFE+rSFLC was able to detect M-protein across all subgroups of patients. In 61 patients, rSFLC values were within ...
Transient neonatalacquired von Willebrand syndrome (AVWS)has been observed peripartum. Its clinical management is analogous to monoclonal gammopathy of undetermined significance (MGUS) of the mother since it is the consequence of transplacental transfer of maternal IgG antibodies (Simone et al.1968; Nag...