IGF-1的水平受青春发育情况、年龄、性别、营养等多个因素影响。Hormone Research上发表的一项研究揭示了健康儿童血清IGF-1水平百分位图及儿童不同发育阶段的IGF-1水平变化趋势。结果显示在青春期早期,儿童血清IGF-1水平随年龄逐渐上升,但变化趋势较缓慢,在14岁前后达到高峰,...
食用本文前,先熟悉几个中英文对应关系: 生长激素——GH(growth hormone) 生长因子——GF(growth factor) 胰岛素样生长因子-Ⅰ—— IGF-Ⅰ(insulin-like growth factors-1) 胰岛素样生长因子结合蛋白-3——IGFBP-3(insulin-like growth factor binding protein-3) 生长因子(GF)是一个庞大集团的统称,它旗下有很多...
食用本文前,先熟悉几个中英文对应关系: 生长激素——GH(growth hormone) 生长因子——GF(growth factor) 胰岛素样生长因子-Ⅰ—— IGF-Ⅰ(insulin-like growth factors-1) 胰岛素样生长因子结合蛋白-3——IGFBP-3(insulin-like growth factor binding protein-3...
IGF-1又叫做Somatomedin-C,是一种胜肽类生长因子,身体有多种组织可制造IGF-1,但最主要的来源是肝脏。肝脏在生长激素(Growth hormone)的刺激控制下,合成并分泌IGF-1。 生长激素(Growth hormone; GH)由脑下垂体前叶分泌,主要的功能在控制人体内部细胞,骨骼,肌肉的生长和维持器官正常功能。 分泌出来的GH进入血液,数...
Growth Hormone & IGF Research is a forum for research on the regulation of growth and metabolism in humans, animals, tissues and cells. It publishes articles on all aspects of growth-promoting and growth-inhibiting hormones and factors, with particular emphasis on insulin-like growth factors… Vie...
【学术前沿】PNAS | 岳锐课题组揭示骨髓来源IGF-1调控成体骨骼维持与损伤修复 胰岛素样生长因子（Insulin-like growth factor I，IGF-1 ）是一种具有促生长作用的多肽类物质，其分泌细胞广泛分布于肝脏、肾脏、心、肺和大脑等多个组织【1】。生长激素（Growth hormone，GH）/IGF-1信号轴作为一条关键的内分泌通路...
Growth Hormone & IGF Research Genetic and epigenetic variability in the gene for IGFBP-3 ( IGFBP3 ): Correlation with serum IGFBP-3 levels and growth in sh... DKDCM Van,AEJ Hendriks,WA Ester,... 被引量: 37发表: 2009年 Genetic and epigenetic variability in the gene for IGFBP-3 (IGFBP...
关键词胰岛素样生长因子;转基因动物,基因敲除;宫内生长发育迟缓中分类号R-322文献标识码A文章编号1008-8830(2000)03-0237-02 生长激素(Growth Hormone, GH)是出生后 2、体格生长调节的主要激素,GH通过诱导肝脏及其他靶细胞产生生长介素(somatomedins)而发挥其生物学活性。生长介素因其在结构上与胰岛素前体有高度同源...
1.(http://en./wiki/Insulin-like_growth_factor_1原文: Insulin-like growth factor 1 (IGF-1) that was once called somatomedin C, is a polypeptide protein hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in...
The bioactivity of the growth hormone-insulin-like growth factor (IGF) system is reduced in Turner syndrome and may explain the reduction seen in final height. We compared levels of free and total IGF-I, immunoreactive and Western ligand blot IGF-binding protein (IGFBP)-3, and IGFBP-3 proteo...