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此次SC0062获得CDE授予突破性治疗品种的认定是基于一项名为2-SUCCEED的临床II期试验中IgA肾病队列的优异结果,临床数据显示SC0062与安慰剂组相比能够显著降低蛋白尿,且在不同剂量组间呈现出明确的量效关系,结果具有显著的临床意义和统计学意义。 SC0062项目2-SUCCEED临床II期研究旨在分别评估SC0062胶囊在IgA肾病队列、...
目的:了解IgA肾病肾病综合征的临床和病理的特点及其与预后的关系。方法 :观察 72例经肾活检确诊为IgA肾病且表现为肾病综合征的患者的临床表现、实验室检查、病理改变... 杨剑辉,张纪芸,王艳侠 - 《中国中西医结合肾病杂志》 被引量: 9发表: 200...
Adnot S.ServiceKargerNephronRostoker G,Desvaux-Belghiti D,Pilatte Y, et al.Immunomodulation with low-dose imm-unoglobulins for moderate IgAN and Henoch-Schonlein purpura. Preliminary results of a prospective uncontrolled trial.Nephron. 1995...
目的探讨血清IgA(IgA)升高的IgA肾病患者临床生化指标及病理牛津分型的关系。方法将136例IgA肾病患者根据血清IgA是否升高分为血清IgA升高组及IgA正常组。收集患者的性别、年龄等一般资料,临床生化指标如肾功能、24 h尿蛋白定量、血尿等进行分...
Wilschut J, de Haan A, Geerligs HJ, Huchshorn JP, van Scharrenburg GJM, Palache AM, et al. Liposomes as a mucosal adjuvant system: an intranasal liposomal influenza subunit vaccine and the role of IgA in nasal anti-influenza immunity. J Liposome Res 1994;4:301-14....