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Although the pathogenesis of immunoglobulin A (IgA) nephropathy and Henoch-Schnlein nephritis (HSN) remains uncertain, there is substantial evidence that they are immune complex–mediated diseases. Recently, Haemophilus parainfluenzae antigens were shown in the glomerular mesangium of adult patients with...
此次SC0062获得CDE授予突破性治疗品种的认定是基于一项名为2-SUCCEED的临床II期试验中IgA肾病队列的优异结果,临床数据显示SC0062与安慰剂组相比能够显著降低蛋白尿,且在不同剂量组间呈现出明确的量效关系,结果具有显著的临床意义和统计学意义。 SC0062项目2-SUCCEED临床II期研究旨在分别评估SC0062胶囊在IgA肾病队列、...
Adnot S.ServiceKargerNephronRostoker G,,Des vaux-BelyhitiD,Pilatte Y,et al.Immunomodulationlow-dose immunoglobulins for moderate IgA nephropathy and Henoch-Schênlein purpura. Nephron . 1995Rostoker G, Desvaux-Belghiti D, Pilatte Y, et al: Immunomodulation with low-dose immunoglobulins for ...
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Wilschut J, de Haan A, Geerligs HJ, Huchshorn JP, van Scharrenburg GJM, Palache AM, et al. Liposomes as a mucosal adjuvant system: an intranasal liposomal influenza subunit vaccine and the role of IgA in nasal anti-influenza immunity. J Liposome Res 1994;4:301-14....
Clin. Med. 2021, 10, 2159 3 of 20 IgG serology was performed at each bi-weekly sampling point together with a series of online questionnaires [2]. Inclusion criteria included people aged 18 and over and capable of providing informed consent that, at inclusion, were either (i) SARS-CoV-2...