Significance was tested with paired t-test. *** = p < 0.001; glycan code: H = hexose (mannose or galactose); N = N-acetylglucosamine; F = fucose; S = sialic acid Full size image IgA1 and IgA2 plasma cells display similar glycoenzyme expression To investigate ...
Full size image GO analysis of the module showed that the CC terms of the DEGs were mostly enriched in integral component of plasma membrane, cell surface and plasma membrane (Figs. 5a, 6a). The MF terms were mainly enriched in superoxide-generating NADPH oxidase, receptor activity and protein...
Dexmedetomidine was not clastogenic in the in vitro human lymphocyte chromosome aberration test in the absence or presence of human liver S9 metabolic activation, however, a weak clastogenic response was noted in the presence of rat liver S9 metabolic activation. Dexmedetomidine was not clastogenic in...
but it is usually <1g/24h, serum creatinine and BUN are in normal levels in most of the patients. Serum levels of IgA may be increased in many patients, but this increased level does not constitute a test with high sensitivity or specificity for the diagnosis. There are no alterations in...
Significance was tested with paired t-test. *** = p < 0.001; glycan code: H = hexose (mannose or galactose); N = N-acetylglucosamine; F = fucose; S = sialic acid Full size image IgA1 and IgA2 plasma cells display similar glycoenzyme expression To investigate ...
Full Name Permanent Residential Address U.S.Tax ID Number (TIN) 1010161-E_2015-03 Page 3 of 6 IGA DECLARATION FOR ACTIVE/PASSIVE NON-FINANCIAL FOREIGN ENTITY (NFFE) (ENTITY ACCOUNT HOLDERS ONLY) I/We declare that: • The information provided on this form, and all statements made in ...
Continuous variables were analyzed using the Mann–Whitney U test, and categorical variables were analyzed using Fisher’s exact test. Multivariate logistic regression analysis with stepwise forward selection was performed using variables identified as significant (P < 0.05) in univariate analyses. Th...
Full size image ROC curve analysis of 10 hub genes in predicting IgAN The receiver operating characteristic (ROC) curve, a fundamental tool for diagnostic test evaluation, was brought to explore the diagnostic value of identified hub genes, of which area under the curve (AUC) served as a quant...
aclinicallyapplicabletest.and1,920controls.Thisstudyidentifiedfive CapillaryelectrophoresiscoupledwithsusceptibilitylociforIgAN,includingthree time-of-flightmassspectrometryistheonlydistinctsignalswithintheMHClocusonchro- technologythathasidentifiedrenaldiseasesonmosome6p21:(a)intheHLA-DRB1,-DQA1, thebasis...
IC50: the lower the IC50, the stronger the neutralization capability. Concentration (unit/mL) listed in log10 form. Both antibody concentration comparison and IC50 statistical calculations are measured using Mann–Whitney unpaired, nonparametric test; the figure is shown as geometric mean and geometric...