There are five different heavy chain types, IgA, G, M, D and E, which differ in the constant-region amino acid sequence and the carbohydrate content. Each individual plasma cell secretes only one heavy chain type associated with one light chain type. On rare occaisions, the formation of ...
Protein L is an immunoglobulin-binding protein expressed by the anaerobic speciesPeptostreptococcus magnus[1]. Protein L binds specifically to the variable domain of Ig kappa light chain without interfering with the antigen-binding site [2]. It binds strongly to human kappa light chain subclasses I...
These transgenic mice contains human immunoglobulin genes and inactivated mouse heavy chain and kappa light chain genes (Bristol-Myers Squibb). Transgenic mice were immunized weekly with 10 mg of SARS-CoV spike protein and adjuvants for 6–8 weeks. Hybridomas were generated following a standard ...
1-O-Methylnataloe-emodin 103392-51-4 中文名: 分子式:C16H12O5 Humankappaimmunoglobulinlightchain,κ-IgLCELISAKit 人球蛋白轻链kappa抗体(κ-IgLC)ELISA试剂盒 96T/48T 进口分装 Sennoside B 128-57-4 中文名:番泻苷B 分子式:C42H38O20 Humandynamin2,DNM2ELISA试剂盒人发动蛋白2(DNM2)ELISA试剂盒规...
Prognostic Impact Of Serum Heavy/Light Chain Pairs In Patients With MGUS and Smoldering Myeloma: Long-Term Results From a Single Institution Background Asymptomatic monoclonal gammopathies, such as monoclonal gammopathy of undetermined significance (MGUS) and smoldering myeloma (SMM), are clinical condit...
The clinicopathological characteristics and outcomes of IgA nephropathy with predominant lambda or kappa light-chain deposition IgA nephropathy (IgAN) patients with monoclonal light-chain deposition may be at potential risk of hematological progression. However, whether the clinical... S Sun,W Di,R Li...
In IgA multiple myeloma (MM), monoclonal (M)-spike quantification by serum electrophoresis (SEP) encounters some limitations. Heavy/light chain (HLC) assay is a novel quantitative immunoassay allowing the measurement of IgAk and IgA位 concentrations. The aim of this study was to assess the ...
Evaluation of Double M-Band on Serum Protein Electrophoresis Simulating Biclonal Gammopathy: A Case ReportElectrophoresisMonoclonal P Jain,R Choudhary,AK Harith,... - 《Indian Journal of Clinical Biochemistry》 被引量: 0发表: 2021年 POEMS Syndrome with IgG-lambda/IgA-kappa Biclonal Gammopathy and...
Assessment of the diagnostic performances of IgA heavy and light chain pairs in patients with IgA monoclonal gammopathy Objectives Preliminary results of the IgA Hevylite™ assay including the establishment of the 95% reference interval and assessment of the specificity an... F Wolff,F Debaugnies...
In the physiological conditions, human IgA1 exhibits the O-glycosylation on the serine (Ser) and threonine (Thr) residues located in the hinge region of the IgA1 heavy chain. These O-glycan side chains exist as disaccharide with a primary N-acetylgalactosamine (GalNAc) and a secondary β...