so that's actually normal to see in IgA nephropathy. I don't know how many percentage of cases, but it's pretty typical to see a little bit bright staining for lambda. This does not imply a monoclonal process and just, you know, when you see that bright staining. like if you read ...
BMC NephrologyKitazawa, A.; Koda, R.; Yoshino, A.; Ueda, Y.; Takeda, T. An IgA1-lambda-type monoclonal immunoglobulin deposition disease associated with membranous features in a patient with IgG4-related kidney disease: A case report. BMC Nephrol. 2018, 19, 330. [CrossRef] [PubMed]...
Several immunological abnormalities were found in a patient with mixed axonal and demyelinating neuropathy in association with a prominent monoclonal IgA-lambda band in his serum. He had antibodies to the major LM1 ganglioside of human nerve that were restricted to the IgA class, but they were ...
The diagnosis was IgGlambda type multiple myeloma and concurrent IgAkappa type monoclonal gammopathy of undetermined significance with type I cryoglobulinemia. A skin biopsy taken from an involved site showed amorphous eosinophilic material occluding small vessel lumens. There was a good response after ...
A Rare Case of Proliferative Glomerulonephritis with Monoclonal IgA Lambda Deposits with Crescentsdoi:10.1681/ASN.20233411S1779bNeeharik MareeduUPMC Western Maryland, Cumberland, MD;Ravi T. PillaVirginia Commonwealth University Health System, Richmond, VA .American Society of Nephrology...
– This observation allows to display the particularities of IgD myeloma: remarkable preponderance of lambda-type light chains, small or no visible monoclonal spike on serum electrophoresis, frequent extraosseous spread of tumor, renal failure and presence of osteolytic lesions. Over the last years, ...
Light and heavy chain deposition disease is a very uncommon subtype of monoclonal immunoglobulin deposition disease and only small numbers of cases of IgA kappa LHCDD have been reported. The authors thank the HUPNVS of Assistance Publique Hpitaux de Paris for funding publication fees.doi:10.1111/...
IgA nephropathy (IgAN) patients with monoclonal light-chain deposition may be at potential risk of hematological progression. However, whether the clinical characteristics of the patients with predominant lambda or kappa light-chain deposition were consistent with monoclonal light-chain deposition is ...
IgA; monoclonal antibodies; human antibodies; poliovirus; circulating vaccine derived polioviruses; cVDPV; On-Cell mAb Screening; OCMS™; hybridoma methods1. Introduction The oral attenuated poliovirus vaccine (OPV) is the most effective vaccine for eradicating wild Polio Virus (PV). Yet, OPV can...
antibodies Article Human IgA Monoclonal Antibodies That Neutralize Poliovirus, Produced by Hybridomas and Recombinant Expression Rama Devudu Puligedda 1 , Vladimir Vigdorovich 2 , Diana Kouiavskaia 3, Chandana Devi Kattala 1, Jiang-yang Zhao 4, Fetweh H. Al-Saleem 1, Konstantin Chumakov 3, D...