Pelanda R, Schaal S, Torres RM, Rajewsky K. 1996. A prematurely expressed Igκ trans- gene, but not VκJκ gene segment targeted into the Igκ locus, can rescue B cell develop- ment in λ5-deficient mice. Immunity 5:229-39Pelanda, R., S. Schaal, R.M. Torres, and K. Rajewsky...
Ig Heavy Chain Gene Rearrangements in T-Cell Acute Lymphoblastic Leukemia Exhibit Predominant Dh6-19 and Dh7-27 Gene Usage, Can Result in Complete V-D-J Rearrangements, and Are Rare in T-Cell Receptor αβ Lineage Author links open overlay panelTomasz Szczepański, Marja J. Pongers-Willem...
betaig-h3 is a transforming growth factor-beta-inducible cell adhesion molecule that has four characteristic homologous repeated domains. We made recombinant betaig-h3 proteins, which were highly active in mediating human corneal epithelial (HCE) cell adhesion and spreading. The 2nd and the 4th repe...
The pVKR3-83neo targeting vector (Figure 1a) was designed to introduce the rearranged 3-83κ IgL gene into the Igκ locus at the site where a naturally rearranged κ gene would be located. The rearranged Vκ3-83–Jκ2 region (Nemazee and Bürki 1989), with its own promoter, was origi...
Diversity and somatic hypermutation of the Ig VHDJH, V kappa J kappa, and V lambda J lambda gene segments in lymphoma B cells: relevance to the origin of t... et al.Diversityand somatic hypermutation of the Ig VHDJH,V kappaJ kappa,and V lambda J lambda gene segments inlymphoma B ...
(SLC)-deficientbelieved to serve as a checkpoint that signals that amice carrying either a VkJk–Ck transgene under theproductive m chain has been expressed. Mice unablecontrol of the k promoter and intron enhancer or ato express either the membrane form of the IgH chainVkJkgene segment ...
assay. These results pointed out that transcription factors Sp1 andCREB regulate the transcription of the cGAS gene.1. IntroductionVirus infection is a huge threat to human health. The occurrence ofsome cancers is related to the infection of certain viruses. The innateimmune system f i ghts ...
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Charreire, JeannineTaylor & FrancisAutoimmunityMignon-Godefroy K, Ropars A, Bedin C, Charreirc J. Ig VH gene family usage in spleen cells of CBA/J mice immunized with experimental autoimmune thyroiditis (EAT) inducer antigens. Autoimmunity 1993; 14:189-95....
1996. A prematurely expressed Igκ trans- gene, but not VκJκ gene segment targeted into the Igκ locus, can rescue B cell develop- ment in λ5-deficient mice. Immunity 5:229-39Pelanda, R., S. Schaal, R.M. Torres, and K. Rajewsky. 1996. A prematurely expressed Ig(kappa) ...