doi:10.1016/S1873-9946(09)60235-XM.ChaparroandJ.PanésandV.GarciaandM.SDOSJournal of Crohn's and Colitis
For this purpose, the IFX drug concentrations in the blood are tested before the next infusion. In addition to the therapeutic benefits, TDM of infliximab helps reducing the cost of treatment. Result TDM of infliximabTherapy optimization / action ...
cult to justify the use of mycophenolate mofetil in the treatment of patients with IBD at this time. Methotrexate Methotrexate has been used in clinical medicine for nearly half a century. This agent induces clinical response more rapidly than 6-MP or AZA in patients with IBD. Over the course...
” significantly increased incidence of serious infection ranging 1.2-2.78 times that of control (treatment with methotrexate) [than infliximab].” [2015] “antitumor necrosis factor agents, such as infliximab, have variable drug clearance across individuals, mostly related to the disease burden at the...
There are some compiler options that allow you to control the treatment of such numbers, such as "denormals-are-zero", "flush-to-zero", etc. Translate 0 Kudos Copy link Reply JohnNichols Valued Contributor III 01-22-2024 11:09 AM 3,106 Views Now DEN makes sense - thanks -...
Patients receiving IFX treatment often have to leave work/school in order to be treated in the morning. This may be inconvenient for the patients and give capacity problems for the infusion unit at the out-patient clinic. The aim of the study was to investigate if patient-controlled timing ...
In the past decade a shift in the treatment paradigm of IBD has ensued. The availability of drugs capable of inducing mucosal healing, combined with the recognition that IBD is not an intermittent disease, but rather a progressive one causing bowel damage and disability, led us to......
Results data were obtained from a 12-week trial in which patients were randomised to receive algorithm-based therapy (based on levels of IFX and anti-IFX antibodies at treatment failure) or intensified IFX (5mg/kg every 4weeks). At 20-week follow-up, response and remission rates were ...
To individualize timing of infliximab (IFX) treatment in children and adolescents with inflammatory bowel disease (IBD) using a patient-managed eHealth pro... K Carlsen,G Houen,C Jakobsen,... - 《Inflammatory Bowel Diseases》 被引量: 5发表: 0年 SPARC64 XIFX: FUJITSU'S NEXT-GENERATION PROCES...
Methods: Serum concentrations of IFX and antibodies to IFX (ATIs) were measured in patients with IBD at a single center using an enzyme-linked immunosorbent assay and radioimmunoassay. Patient, disease, and treatment characteristics were retrospectively collected along with laboratory values. Pharmacokineti...