IFN-γ + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38mapk in a mouse macrophage cell line. Am J Physiol Cell Physiol 2001; 280: C441-50.Chan ED;Riches DW.IFN-gamma + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38 (mapk)in a mouse macrophage cell...
CXCL10 is typically produced by myeloid cells in response to IFN-, as well as by neutrophils, though the latter require a costimulation with IFN- and LPS. In this study, we investigated the molecular mechanism(s) whereby IFN- and TLR4 ligation synergize to induce CXCL10 expression in ...
Compared with IFN-gamma(+/+) mice, IFN-gamma(-/-) mice produced lower levels of mouse thyroglobulin-specific autoantibodies after immunization with MTg and LPS. These results indicate that cells from both IFN-gamma(+/+) and IFN-gamma(-/-) donors can induce severe granulomatous EAT. However...
Injections of LPS plus IFN- expanded these populations within the spleen but not LN leading to the block of the proliferation of CD8+ T cells. At the same time, their capacity to develop into DC was impaired. Together, our data suggest that spleens of healthy mice contain two subsets of ...
After stimulation with LPS, TNF-α and IFN-γ, calcium increase was mainly caused by Y5 receptor. The modulation of the NPY system by LPS, TNF-α and IFN-γ, and the NPY-induced calcium signaling suggest a role for NPY during the inflammatory response. 展开 ...
Regulatory role of ATF3 on NO production in LPS/IFN‐γ‐treated macrophages In the present study, we examined the regulatory role of ATF3 on inducible nitric oxide synthase (iNOS) expression in LPS/IFN-γ-treated macrophages. ATF3 knockdown enhanced NO in macrophages. Western blot and RT-...
This ISRE is a multifunctional motif that also binds the LPS-inducible factor kappaBF-A and is located within the kappaBS region, which confers B cell specific activity to this enhancer. However, since the expression of IRF-1 is not restricted to B cells, it must not be sufficient for ...
人脂多糖/内毒素(LPS)ELISA试剂盒 规格: 96T/48T Human Lipopolysaccharides,LPS ELISA Kit 人脂蛋白脂酶(LPL)ELISA试剂盒 规格: 96T/48T Human lipoprotein lipase,LPL ELISA Kit 人脂蛋白α(Lp-α)ELISA试剂盒 规格 53 (Ser20) 磷酸化肿瘤抑制基因P53抗体 Anti-phospho-P53 (Ser315) 磷酸化肿瘤抑制基因P53...
IFN-γ can alleviate symptoms of sepsis by restoring LPS-induced TNF-α production and HLA-DR expression in patients. This recovers macrophage activity and helps in clearance of sepsis [94]. IFN-γ therapy has been shown to successfully contain the damaging consequences of fibrosis. It ...
: IFN-${\gamma}$ . IFN-${\gamma}$ DNA IFN-${\gamma}$ STAT1 . : recombinant IFN-${\gamma}$ (100, 1000IU/ml) HLA-DR CD64 , . LPS TNF-${\alpha}$ IFN-${\gamma}$ LPS TNF-${\alpha}$ . , . IFNgR1 STAT1 . : IFN-${\gamma}$ . BCG NTM IFN-${\gamma}$ ....