Sepsis is a leading cause of morbidity and mortality worldwide, and is among the most expensive health conditions in the United States. Sepsis has recently been defined as a dysregulated host response to an ongoing ...
Sepsis and septic shock are common diseases with high mortality rates and asurvival rate that decreases with every hour of delayed therapy. While definitions are valid and published, even the best sepsis score is not helpful if the criteria are not measured regularly in case of suspected sepsis....
>>>Colonization alone is not necessarily an infection, but rather signifies the potential for infectionInflammation: protective mechanism of body tissues in response to invasion or toxins produced by colonizing microorganisms bacteremia vs ...
7. Alhazzani W, Møller MH, Arabi YM, et al. Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19). Crit Care Med. 2020;48(6):e440-e469. doi:10.1097/CCM.0000000000004363 8. Yang X, Yu Y, Xu J, et al. Clinical ...
Ifinatamab: 一种CD276抑制剂药物,由Daiichi Sankyo, Inc. (Daiichi Sankyo, Inc.)公司最早进行研发,目前全球最高研发状态为临床前,作用机制: CD276抑制剂(CD276抗原抑制剂),在研机构: Daiichi Sankyo, Inc.。
In KEYNOTE-869, when KEYTRUDA was administered in combination with enfortumab vedotin to patients with locally advanced or mUC and who are not eligible for cisplatin-based chemotherapy (n=121), fatal adver...
p pBackground/p pSepsis and complications to sepsis are major causes of mortality in critically ill patients. Rapid treatment of sepsis is of crucial impor... JU Jensen,B Lundgren,L Hein,... - 《Bmc Infectious Diseases》 被引量: 78发表: 2008年 A new approach to determine the susceptibili...
By contrast, “probable” IFSD indicates an immunocompromised host with ongoing fungal sepsis originating from the respiratory tract, the urinary tract, the gastrointestinal tract, and the central nervous system, whereas “possible” IFSD is preferred classification based on appropriate host factors and...
This is mediated via tumor necrosis factor α (TNF-α) and other inflammatory mediators released by Kupffer cells during sepsis and/or inflammation related to native disease or surgery [68]. While several hypotheses have been proposed to explain the pathogenesis, none have been conclusive to-date...