1.首页:iedb.org/ 如图所示,首页除基本信息介绍外分为三个功能模块: 根据表位性质如是否线性、特定序列、间断序列、是否多肽、样本信息、MHC类型、宿主和相关疾病检索已入库的表位信息 预测新抗原表位,具体通过判断其与MHC结合能力、与MHC加工相关性、结合后免疫原性来实现 表位分析工具,可用来分析抗原表位在人群中的...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook AcronymDefinition IEDBImmune Epitope Database(molecular targets of the immune system) IEDBInternational Economic Data Bank(Crawford School of Economics and Government; Australian National University Supercomputer Facility) ...
MHC binding prediction Epitope prediction B-cell epitope prediction T-cell epitope prediction IEDB is regularly updated with new data and features, ensuring that it remains a valuable tool for immunologists and vaccine developers worldwide. Immune Epitope Peptides In the scientific community, the IEDB...
在上一条的表位梳理表格中,可以很明显地发现,野生型KRAS序列的表位主要集中在前半段,而突变特异性表位主要集中在突变位点后半段。因此,如果要设计一个突变特异性的KRAS治疗性疫苗抗原序列,就可以只关注后半段的11/12个氨基酸长度即可。 把表位长度确定好之后,重新将G12D、G12V、G12R、G13D重新进行IEDB的MHC-I...
MHC-NP(http://tools.iedb.org/mhcnp)(6)是一种预测由I类MHC途径天然加工并与I类MHC分子结合的肽的工具。 该工具可以预测六个人类和两个小鼠MHC等位基因的MHC I配体。 同样,MHCII-NP(http://tools.iedb.org/mhciinp)(7)是预测天然加工的MHC II配体的工具。 这些工具是通过训练从MHC分子洗脱的天然加工肽...
Last commit date Latest commit iskandr MHC diff Oct 8, 2024 cae7b52·Oct 8, 2024 History 187 Commits pepdata MHC diff Oct 8, 2024 tests adding more column helper Jun 7, 2024 .gitignore added refseq to tcga Mar 13, 2014 .travis.yml ...
The IEDB houses epitope-specifc experimental assays.That is, every assay re,ects the binding o, an epitope-specifc T cell receptor(TCR),antibody or MHC molecule to an experimentally tested antigen or epitope.The struc-ture entered as the epitope is limited to the exact entity that was actual...
Epitopes are defined as the molecular structures interacting with specific receptors of the immune system such as antibodies, MHC, and T cell receptor mole... Alessandro Sette,Huynh-Hoa Bui,John Sidney,... - Pattern Recognition in Bioinformatics, International Workshop, Prib, Hong Kong, China, ...