The guidelines were reviewed in a session at the American Society of Health-System Pharmacists titled "Beyond the Top Line: A Point-Counterpoint Discussion of the 2020 Antimicrobial Resistant Gram-Negative Infection Treatment Guideline." In part 2 ...
they should be considered as two positive confirmatory samples. Uncommon contaminants or virulent organisms (e.g. Staphylococcus aureus or Gram-negative rods) are more likely to represent
when 21 days was permitted EOT visit to occur within 5d of end of treatment EOS visit to occur 7-30d after last day of study drug Coverage for Gram-negative organisms was required (cefepime or other antibiotic NOT active against MRSA) Reference(s): Colhoun HM, Betteridge DJ, Durrington PN...