The expression of hub genes was assessed using clinical data extracted from the Human Protein Atlas (HPA) database. Results A total of 139 and 13 DEGs were found to be upregulated and downregulated, respectively, in CESC. The six hub genes, namely, SELP, PIM2, CCL19, SDS, NRP1, and ...
In other words, we can identify 102 coordinates of \(x=y\) or, equivalently, 102 edges of the graph, such that the sex of the corresponding subject can be expressed by the sign of the linear expression \(w\cdot x + b\) . The value of b and the 102 non-zero coordinates of w ...
Deep learning sequence-based ab initio prediction of variant effects on expression and disease risk. Nat. Genet. 50, 1171–1179 (2018). Article CAS PubMed PubMed Central Google Scholar Zhu, X. & Stephens, M. Large-scale genome-wide enrichment analyses identify new trait-associated genes and...
Movie scripts are technical documents created by screenwriters and serve as an essential reference for filmmakers. Blocks of text divided into scene headers, scene descriptions, speakers, and utterances are parts of a standard movie script. The critical point is the different indentations used for e...
After designing and building the vector harboring the POI, an E. coli expression strain must be chosen. There are many strains that have been engineered for the purpose of heterologous protein expression which are reviewed here [13]. The choice of strain can have a profound impact on protein ...
An SV involves two breakpoints representing the fusion of two respective genomic coordinates. Some of the individual steps involved in our SV-expression integrative analysis approach include constructing a gene-to-sample breakpoint pattern matrix, linear regression modeling to associate altered expression ...
tricyclic and the like. Also included in this expression are the benzoheterocyclic rings and other fused heterocyclic ring systems. If nitrogen is a ring atom, the present invention also contemplates the N-oxides of the nitrogen containing heteroaryls. Non-limiting examples of heteroaryls include th...
In another embodiment, the recombinant vector construct comprises an expression vector usable in eukaryotes and/or prokaryotes. An expression vector contains a promoter which can be linked functionally to a polynucleotide sequence so that a protein encoded by said polynucleotide sequence is synthesized in...
Potential interview participants were recruited through an online expression of interest survey, advertised through the primary author’s social media (Facebook, Twitter, and LinkedIn), which assessed eligibility for an interview through questions around demographics and self-identified subcultural identities...
The functions of p53 and the retinoblastoma-related gene Rb2/p130 have been studied in nasopharyngeal cancer cell lines9,10. DNA and mRNA expression profiling analyses were used to evaluate the amplification and 1College of Biology and Food Engineering, Jilin Engineering Normal University, Changchun...