To validate our methods and to compare to prior methods we used a dataset from the United Medical Language System (UMLS) [29] termed the Medication Reference Terminology (Med-RT) [1]. Med-RT includes drug names and the indications they are known to treat, referred to as “may-treat” re...
The effects of clinical decision support systems on medication safety: an overview. PloS one. 2016;11(12):e0167683. PubMed PubMed Central Google Scholar Kwok R, Dinh M, Dinh D, Chu M. Improving adherence to asthma clinical guidelines and discharge documentation from emergency departments: ...
The post-treatment microbiological test results also confirm the effectiveness of the medication. Despite the diagnosis using mNGS offers a valuable reference for the treatment of polymicrobial pulmonary infection, our study is still subject to the following limitations. Firstly, as a case report with ...
There are many tools available to help the health care team assess medication appropriateness; however, none of the currently available tools have been validated in the geriatric oncology population. Older adults with cancer are at increased risk for ADRs and potentially inappropriate medications (PIMs...
All PD patients were in an off-medication state during the experiment. To minimize noise in the data, the initial and final seconds of the ML_CoPT and AP_CoPT were discarded. Data points with absolute robust Z-scores exceeding 3 were identified as outliers and replaced with the averages of...
In contrast, the proportion of individuals receiving intravenous medication significantly rose in C2 and C3, along with the number of individuals not following any treatment. The majority of individuals in C1 and C4 were satisfied with their DMTs. In contrast, an opposite trend was observed in C2...
We also examined if there is association between dynamic connectivity and medication. For the daily antipsychotic dose chlorpromazine (CPZ) equivalents, we applied a multiple linear regression model to test the association between the strengths of the important connectivity features in the dominant state...
Maraviroc, an antiretroviral medication [38], inhibited the CCR5 receptor in the co-culture model. When CCR5 was blocked, the protein expression of AKT, p-AKT, Sp1, c-Myc, and CD44 decreased (Fig. 4D). Mithramycin (MIT) is an antineoplastic antibiotic used to treat testicular cancer, ...
Drug-drug interactions are one of the main reasons for adverse events associated with medication. The traditional pharmacokinetic methods for studying DDIs are inadequate for discovering potential side effects or explaining complicated interaction mechanisms. Furthermore, the complex components for many compl...
We then validated the resulting subtypes using cortical thickness, white matter integrity as measured by fractional anisotropy (FA), polygenic risk scores (PRS), and risk gene expression tissue profile. We also examined the effects of medication status on symptom severity to elucidate possible ...