Alternative splicing is crucial for cancer progression and can be targeted pharmacologically, yet identifying driver exons genome-wide remains challenging. We propose identifying such exons by associating statistically gene-level cancer dependencies from
Melnica locality in Mariovo is an output zone of a hypogene karst system, where caves and cave remnants developed in calcite marble, dolomite marble and carbonate breccia, and a small lukewarm Melnica Spring, are found (Supplementary Fig. S2). Prov- alata Cave is a small fossil cave and...
Both temperature and salt may be varied, or either the temperature or the salt concentration may be held constant while the other variable is changed. For example, hybridization using DNA or RNA probes or primers can be performed at 65° C. in 6×SSC, 0.5% SDS, 5× Denhardt's, 100 ...
The same is done with the correlation of spring discharges and SO4 concentrations, but in a log-log scale. Annual water and solute balances of both springs are simply expressed by their annual sums. Now, we can directly evaluate if our models are able or fail to reproduce the specific ...
1. A method of identifying a layer boundary of a subterranean formation, comprising: transmitting an acoustic signal from a transmitter into a borehole of the subterranean formation; receiving the acoustic signal at a receiver coupled to the downhole tool and spaced from the transmitter; logging an...
respectively. The Bland–Altman difference vs. average plots cone shaped distributions observed for both DBS and plasma indicate that the measurement error between the methods are proportional but not constant and that a weighted Deming regression approach was required. Deming regression revealed good agr...
Euler–Bernoulli beams and a spring-mass system are used to simulate bridge and vehicle, respectively. It must be mentioned that the road surface roughness and damping coefficient are not considered in this study. In addition, a frequency extraction method was proposed to more accurately filter ...
with anti-SARS-CoV-2 spike antibodies. (d) Affinity analysis: interference shifts over time, reflecting the interference change caused by different concentrations. (e) Steady-state analysis: Response over the concentration of Model-S. (d,e) for the calculation of the affinity constant of Model-...
This is true in the modeling processes were beam elements, spring elements, and lumped masses are primarily used, leading to simple mode shapes. However, according to Fang and Perera [24], in complex structures, the correlation between the mode shapes must be taken into consideration, because ...