Saccharomyces cerevisiae YFH7 is one of these P-loop proteins of unknown function. In this work we tried to integrate bioinformatics, structure, and enzymology to discover the function of YFH7. Sequence analysis
Motor disability is a critical impairment in stroke patients. Rehabilitation has a limited effect on recovery; but there is no medical therapy for post-stroke recovery. The biological mechanisms of rehabilitation in the brain remain unknown. Here, using a photothrombotic stroke model in male mice, ...
a, Schematic diagram of the domain structures for the L and Z proteins. Each domain is represented with a unique colour. The CTD of L polymerase is not resolved in the monomeric L–Z complex structures and is only visualized in the dimeric forms of the MACV L–Z and L–Z–vRNA comple...
ProTInSeq is a technique designed to characterize proteomes by sequencing transposon insertions engineered to express a selection marker when they occur in-frame within a protein-coding gene. In the bacterium Mycoplasma pneumoniae, ProTInSeq identifies 83% of its annotated proteins, along with 5 ...
Desiccation is the extreme form of dehydration wherein most of the protoplasmic “free” water is lost and the cell survival relies on the ‘bound’ water associated with the cell matrix. Dehydration is one of the most common environmental stresses to which plants are exposed, and in many ...
Identify the structure from the given description: A cell located in the epidermis that produces melanin. Cells: Cells are the basic units of life which carry out the metabolic activities that keep the organism as a whole alive. Cells arrange themselves into tis...
and ATP. AMP binding to CBS4 enhances its affinity to AMP relative to ADP and ATP. AMP binding, in turn, results in a major structural change promoting the phosphorylation of Thr172 on the α subunit, critical for AMPK activity. In contrast to AMPK, SNF1 is not subjected to AMP regulatio...
View this answer The organelle that produces the bulk of the cell's ATP is the mitochondrion, where the metabolic reactions of the citric acid cycle and the oxidative... See full answer below.Become a member and unlock all Study Answers Start today. Try ...
The characterization of protein-protein interactions (PPIs) is fundamental to the understanding of biochemical processes. Many methods have been established to identify and study direct PPIs; however, screening and investigating PPIs involving large or p
The QT interval is an electrocardiographic measure representing the sum of ventricular depolarization and repolarization, estimated by QRS duration and JT interval, respectively. QT interval abnormalities are associated with potentially fatal ventricular